Minjung Kim

US Patent:

20040002086, Jan 1, 2004

Filed:

Feb 13, 2003

Appl. No.:

10/366990

Inventors:

Cory Abate-Shen - Warren NJ, US
Michael Shen - Warren NJ, US
Minjung Kim - Piscataway NJ, US

Assignee:

University of Medicine & Dentistry of New Jersey

International Classification:

C12Q001/68
G01N033/574

US Classification:

435/006000, 435/007230

Abstract:

The present invention pertains to a monoclonal antibody, or fragment thereof, having an antigen-binding specific region for NKX3.1 and to a hybridoma cell line for producing the monoclonal antibody. The present invention also pertains to a method for detecting the presence of NKX3.1 in a sample. The method comprises (a) contacting a biopsy tissue sample with a monoclonal antibody, or a fragment thereof, having an antigen-binding specific region for NKX3.1, under conditions permitting immunospecific binding between the monoclonal antibody, or a fragment thereof, and NKX3.1 in the sample; and (b) detecting whether immunospecific binding has occurred to detect the presence of NKX3.1 in the sample.

US Patent:

20080108092, May 8, 2008

Filed:

Aug 13, 2007

Appl. No.:

11/837756

Inventors:

Corey Abate-Shen - Warren NJ, US
Michael Shen - Warren NJ, US
Minjung Kim - Piscataway NJ, US

International Classification:

G01N 33/574
C07K 16/18
C12N 5/06

US Classification:

435007230, 530387700, 530391300, 435330000

Abstract:

The present invention pertains to a monoclonal antibody, or fragment thereof, having an antigen-binding specific region for NKX3.1 and to a hybridoma cell line for producing the monoclonal antibody. The present invention also pertains to a method for detecting the presence of NKX3.1 in a sample. The method comprises (a) contacting a biopsy tissue sample with a monoclonal antibody, or a fragment thereof, having an antigen-binding specific region for NIX3.1, under conditions permitting immunospecific binding between the monoclonal antibody, or a fragment thereof, and NKX3.1 in the sample; and (b) detecting whether immunospecific binding has occurred to detect the presence of NKX3.1 in the sample.

US Patent:

20030027226, Feb 6, 2003

Filed:

May 10, 2001

Appl. No.:

09/853121

Inventors:

Cory Abate-Shen - Warren NJ, US
Michael Shen - Warren NJ, US
Minjung Kim - Piscataway NJ, US

International Classification:

G01N033/574
C12N005/06
C07K016/40

US Classification:

435/007230, 530/388260, 435/338000

Abstract:

The present invention pertains to a monoclonal antibody, or fragment thereof, having an antigen-binding specific region for NKX3.1 and to a hybridoma cell line for producing the monoclonal antibody. The present invention also pertains to a method for detecting the presence of NKX3.1 in a sample. The method comprises (a) contacting a biopsy tissue sample with a monoclonal antibody, or a fragment thereof, having an antigen-binding specific region for NKX3.1, under conditions permitting immunospecific binding between the monoclonal antibody, or a fragment thereof, and NKX3.1 in the sample; and (b) detecting whether immunospecific binding has occurred to detect the presence of NKX3.1 in the sample.