As an academic medical center, Cleveland Clinic Florida provides world class care. Our mission is to provide better care of the sick, investigation of their problems, and further education of those who serve. We strive to provide Best-in-Class patient experiences and superior clinical outcomes.
Education:
Medical Schools University Of Vienna Graduated: 1995
2950 Cleveland Clinic Blvd, Weston, FL 33331 111 Cypress St, Brookline, MA 02445 75 Francis St, Boston, MA 02115
Education:
University of Vienna, Faculty of Medicine - Doctor of Medicine
Board certifications:
American Board of Internal Medicine Certification in Internal Medicine American Board of Internal Medicine Sub-certificate in Nephrology (Internal Medicine)
Us Patents
Methods Of Using Anti-Thymocyte Globulin And Related Agents
Nader Najafian - Brookline MA, US Mohamed H. Sayegh - Westwood MA, US Melanie Ruzek - Danielson CT, US Srinivas Shankara - Shrewsbury MA, US John Williams - Hopkinton MA, US Johanne Kaplan - Sherborn MA, US John M. McPherson - Hopkinton MA, US
International Classification:
A61K 35/18 A61K 38/17 A61P 37/00 C12N 5/0783
US Classification:
424 937, 514 12, 4353723
Abstract:
Uses for anti-thymocyte globulin (ATG, e.g., Thymoglobulin) and related compositions are described. In one aspect, ATG and, optionally, TGF-beta are used for in vitro generation of regulatory T cells, which are useful for cell therapy of immune-mediated conditions. In another aspect, ATG is directly administered to a subject at a low dose (e.g., less than 1 mg/kg per day) to treat an immune-mediated condition. The immune-mediated conditions include, for example, transplant rejection, graft-versus-host disease, and autoimmune diseases.