Nancy R Chen

US Patent:

8095514, Jan 10, 2012

Filed:

Feb 4, 2009

Appl. No.:

12/365827

Inventors:

John Beresniewicz - San Mateo CA, US
Jonathan Helfman - Half Moon Bay CA, US
Hsiao-Te Su - Palo Alto CA, US
Nancy Chen - San Jose CA, US
Karl Dias - Foster City CA, US
Graham Wood - El Granada CA, US

Assignee:

Oracle International Corporation - Redwood Shores CA

International Classification:

G06F 17/30

US Classification:

707688, 715853, 715788, 715764, 707999104

Abstract:

Particular embodiments generally relate to displaying database time using a treemap. A set of database time values is determined for a set of dimensions. The database time values measure performance of one or more databases by the time the database takes to respond to a request. The set of database time values is correlated to a set of cells in the treemap. A size of the cell is determined based on the database time value associated with it. For example, the database time value is correlated to an area of the cell. A layout of the set of cells is determined and the treemap is displayed using the layout. For example, the largest values of database time may be shown with the largest sized cells. This makes it easier for an administrator to review and analyze the database performance across multiple dimensions and determine problem areas affecting the performance of the one or more databases.

US Patent:

20080112847, May 15, 2008

Filed:

Nov 14, 2007

Appl. No.:

11/939867

Inventors:

Nancy Yu Chen - Cupertino CA, US

International Classification:

G01N 21/01
B01J 19/00
G01N 33/48

US Classification:

422 58, 422 681, 73 6141

Abstract:

The present invention provides a new and improved collecting and testing device comprising a specimen container for collecting and/or storing specimen, a testing chamber having at least one test element, and a conduit for automatically transferring a portion of the specimen from the specimen container to the testing chamber.

US Patent:

20200316178, Oct 8, 2020

Filed:

Oct 25, 2018

Appl. No.:

16/759201

Inventors:

- Lexington MA, US
Nancy CHEN - Winchester MA, US
Jun HU - Sudbury MA, US
Muthuraman MEIYAPPAN - Lexington MA, US
Thomas Allen MILLER - Wakefield MA, US

Assignee:

SHIRE HUMAN GENETIC THERAPIES, INC. - Lexington MA

International Classification:

A61K 38/47
A61K 31/445
A61K 47/02
A61K 47/12
A61K 47/26

Abstract:

The invention provides a composition of glucocerebrosidase, such as velaglucerase alfa, and isofagomine, in a molar ratio of at least about 1:2.5. Also provided is a use of the composition for treatment of a disorder related to a dysfunction in a GCase pathway. The disorder could be a lysosomal storage disease, such as Gaucher disease, Fabry disease, Pompe disease, a mucopolysaccharidoses, or multiple system atrophy. The disorder could also be a neurodegenerative disorder, such as Parkinson disease, Alzheimer's disease, or Lewy body dementia. The composition can have 0.5 to 5.0 mg/kg of glucocerebrosidase and isofagomine in at least about a 3-fold molar excess to the glucocerebrosidase. The composition can be administered intravenously or subcutaneously.