Kenneth G. Mann - Grand Isle VT Nancy Swords Jenny - Colchester VT
Assignee:
University of Vermont and State Agriculture College - Burlington VT
International Classification:
C12Q 156
US Classification:
435 13, 435184, 435 723, 435 771, 435 4, 530380
Abstract:
The present invention features isolated angiogenesis inhibitors having a molecular weight of between about 40 kDa to 50 kDa and having an amino acid sequence substantially similar to that of the amino acid sequence shown in SEQ ID NO. 2 or SEQ ID NO. 3. Further provided are methods of making and using the angiogenesis inhibitors, e. g. , to inhibit vascularization or to block osteonectin and plasminogen interaction.