Dan Maarten Berger - New City NY, US Minu Dhanjisha Dutia - West Nyack NY, US Darrin William Hopper - New York NY, US Nancy Torres - Nyack NY, US
Assignee:
Wyeth - Madison NJ
International Classification:
A61K 31/53 C07D 487/04
US Classification:
514243, 544184
Abstract:
A pyrazolo[5,1-c][1,2,4]triazine compound of formula A:and pharmaceutically acceptable sats thereof. The multiply-substituted pyrazolo[5,1-c][1,2,4]triazine compounds of the invention selectively inhibit B-Raf kinase activity and are useful for treating disorders mediated by B-Raf kinase.
Thienopyrimidines, Thienopyridines, And Pyrrolopyrimidines As B-Raf Inhibitors
Ariamala Gopalsamy - Mahwah NJ, US Mengxiao Shi - Eastchester NY, US Dan Maarten Berger - New City NY, US Minu Dhanjisha Dutia - West Nyack NY, US Nancy Torres - Nyack NY, US Darrin William Hopper - New York NY, US
Assignee:
Wyeth - Madison NJ
International Classification:
A61K 31/5377 C07D 495/04 C07D 487/04 A61K 31/519
US Classification:
5142342, 544278, 5142601, 544117, 544280, 5142651
Abstract:
The present invention relates to compounds of formula la:and pharmaceutically acceptable salts thereof. The thieno[3,2-d]pyrimidine, thieno[2,3-d]pyrimidine, thieno[3,2-b]pyridine, thieno[2,3-b]pyridine, and pyrrolo[2,3-d]pyrimidine compounds selectively inhibit B-Raf kinase activity and are useful for treating disorders mediated by B-Raf kinase, and for the treatment of cancer.
Bridged, Bicyclic Heterocyclic Or Spiro Bicyclic Heterocyclic Derivatives Of Pyrazolo[1, 5-A]Pyrimidines, Methods For Preparation And Uses Thereof
Jeremy Ian Levin - New City NY, US Darrin William Hopper - New York NY, US Nancy Torres - Nyack NY, US Minu Dhanjisha Dutia - West Nyack NY, US Dan Maarten Berger - New City NY, US Xiaolun Wang - River Vale NJ, US Martin Joseph Di Grandi - Goshen NY, US Chunchun Zhang - River Vale NJ, US Alejandro Lee Dunnick - Long Beach CA, US
Compounds of formula A:and pharmaceutically acceptable salts thereof are described, which selectively inhibit Raf kinase activity and are useful for treating disorders mediated by Raf kinases.
Pyrazolo[1,5-A]Pyrimidine Derivatives And Methods Of Use Thereof
Ariamala Gopalsamy - Mahwah NJ, US Gregory Ciszewski - Pearl River NY, US Mengxiao Shi - New Rochelle NY, US Dan Berger - New City NY, US Nancy Torres - Nyack NY, US Jeremy Levin - New City NY, US Dennis Powell - Cortland Manor NY, US
The present invention relates to pyrazolo[1,5-a]pyrimidine derivatives, compositions comprising an effective amount of a pyrazolo[1,5-a]pyrimidine derivative and methods for treating or preventing cancer, comprising administering to a subject in need thereof an effective amount of a pyrazolo[1,5-a]pyrimidine derivative.
Nov 2006 to 2000 Owner/ManagerPatriot Brick Pavers, LLC DeLand, FL Feb 2005 to Apr 2012 Owner/ManagerCovidien DeLand, FL Mar 1987 to Feb 2002 Buyer
Education:
Stetson University DeLand DeLand, FL May 2001 Master's in BusinessUniversity of Central Florida Orlando Orlando, FL Dec 1999 Bachelor's in Business AdministrationDaytona State College Daytona Beach Daytona Beach, FL May 1995 Associate's in Associate
Walt Disney Resorts Orlando, FL Jun 2005 to May 2014 Housekeeper SupervisorRed Steer Steak House /Golden Corral Cafe Bandoli / Nani's Cafeteria La Familia Chicago, IL Oct 1979 to May 2014 Restaurant HospitalityGCA Group Clermont, FL Custodian/Supervisor
Education:
James Bowen High School Chicago, IL 1981 High School Diploma in 4
Higher Expectations Public School 66 Bronx NY 1947-1954, John Dwyer Junior High School Bronx NY 1954-1957
Community:
Charles Sobelman, Jay Fiering, Roberta Males, Alma Gutierrez, Harriet Goldstein, Rebecca Collazo, Nina Ginsberg, Carol Santiesteban, Mark Breiner, Sheila Rosen
Biography:
Life
I have lived on Long Island for the past32 years. I run my own company, which...
Beres said the three children and adult were passengers in a 2001 Ford Taurus driven by 27-year-old Nancy Torres that was involved in a collision with a 2017 Freightliner driven by Marvin Morales, 36.