Nancy Woolf - Studio City CA, US Howard Greenwald - Penfield NY, US
International Classification:
A61K031/00 A61K009/22
US Classification:
514/001000, 424/468000, 424/423000
Abstract:
A process for treating Alheimer's disease, comprising the steps of administering to a human patient an antagonist of a neurotransmitter receptor which indirectly inhibits phosporylation of microtubule-associated protein-2, and thereafter administering to said patient and anticholinesterase agent. The antagonist of the neurotransmitter binds to a neurotransmitter receptor which phosphorylates said microtubule-associated protein-2 in limbic cells, the antagonist of the neurotransmitter binds to a neurotransmitter receptor which phosphorylates microtuble-associated protein-2 in neocortical cells, and the antagonist binds to said neurotransmitter receptor in said limbic cells at least 1.5 times as much as it binds to said neurotransmitter receptor in said neocortical cells.
Jack Tuszynski - Edmonton, CA Nancy Woolf - Studio City CA, US
International Classification:
A61K039/395 A61K031/337 A61K009/22
US Classification:
424130100, 514449000, 604890100
Abstract:
Disclosed is a device which employs a chemically sensitive cantilever hingably attached to a capsule. The cantilever functions as a switch which regulates the flow of particles into and/or out of the capsule.
Method For Treating Alzheimer's Disease Using Superior Stability Tubulin Consructs
Jack A. Tuszynski - Edmonton, CA Nancy Woolf - Las Vegas NV, US
International Classification:
A61K 38/17
Abstract:
A method of providing a therapeutic benefit to a patient for Alzheimer's Disease (AD) is disclosed. A superior stabilizing-tubulin (SS-tubulin) is administered, either directly or indirectly through gene therapy. Mutated alpha SS-tubulins and mutated beta SS-tubulins are disclosed for use in the method.
Resumes
Adjunct Professor At University Of California, Los Angeles