W. Keith Jones - Fort Thomas KY, US Xiaoping Ren - Mason OH, US Neal Lee Weintraub - Cincinnati OH, US
International Classification:
A61N 1/05
US Classification:
607 46
Abstract:
Methods of inhibiting ischemia-related and ischemia-reperfusion-related injury are provided. Remote administration of a C-fiber activator or TRPV1 agonist or remote electrical stimulation and activation of TRPV1 reduces ischemia-related tissue damage in subjects at risk for ischemia-related tissue damage. In aspects of the invention, remote application of a TRPV1 agonist inhibits ischemia-related cardiac tissue damage. Methods of inhibiting cardiac tissue damage by topically administering the TRPV1 agonist, capsaicin are provided.
Methods Of Preventing Ischemic Injury Using Peripheral Nociceptive Stimulation
W. Keith Jones - Fort Thomas KY, US Xiaoping Ren - Mason OH, US Neal Lee Weintraub - Cincinnati OH, US
International Classification:
A61K 49/06 A61K 31/16 A61K 49/00
US Classification:
424 93, 514627, 424 91
Abstract:
Methods of inhibiting ischemia-related and ischemia-reperfusion-related injury are provided. Remote administration of a C-fiber activator or TRPV1 agonist or remote electrical stimulation and activation of TRPV1 reduces ischemia-related tissue damage in subjects at risk for ischemia-related tissue damage. In aspects of the invention, remote application of a TRPV1 agonist inhibits ischemia-related cardiac tissue damage. Methods of inhibiting cardiac tissue damage by topically administering the TRPV1 agonist, capsaicin are provided.
- Miami FL, US - Augusta GA, US Rudolf Lucas - Martinez GA, US Neal Weintraub - Augusta GA, US
Assignee:
UNIVERSITY OF MIAMI - Miami FL AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. - Augusta GA
International Classification:
A61K 38/16
Abstract:
Described herein are materials and methods for treating dyslipidemia in a mammalian subject in need thereof comprising administering a growth hormone-releasing hormone (GHRH) antagonist or variant thereof to the subject.
Name / Title
Company / Classification
Phones & Addresses
Neal L. Weintraub Director
University of Cincinnati Medical Laboratory College/University