Nicole Black

US Patent:

20210000590, Jan 7, 2021

Filed:

Sep 22, 2020

Appl. No.:

17/027941

Inventors:

- Boston MA, US
- Cambridge MA, US
Nicole Leah Black - Shelby Twp MI, US
Michael J. McKenna - Southborough MA, US
Daniel J. Lee - Brookline MA, US
Jennifer A. Lewis - Cambridge MA, US
John Rosowski - Arlington MA, US
David B. Kolesky - Cambridge MA, US
Alexander D. Valentine - Windham NH, US

International Classification:

A61F 2/18
A61L 27/26
A61L 27/38
A61L 27/54

Abstract:

This disclosure features artificial tympanic membrane graft devices and two-component bilayer graft devices that include a scaffold having a plurality of ribs made of a first material and a plurality of spaces between the ribs filled or made with the first material, a different, second material, a combination of the first and a second materials, or a combination of a second material and one or more other different materials. The bilayer graft devices have two components or layers. One component, e.g., the underlay graft device, can include a projection, and the second component, e.g., the overlay graft device, can include an opening that corresponds to the projection (or vice versa) so that the opening and the projection can secure the two layers together in a “lock and key” manner. This disclosure also features methods of making, using, and implanting the three-dimensional artificial tympanic membrane and bilayer graft devices.

US Patent:

20180042718, Feb 15, 2018

Filed:

Mar 21, 2016

Appl. No.:

15/559582

Inventors:

- Boston MA, US
- Cambridge MA, US
Nicole Black - Shelby Twp MI, US
Michael J. McKenna - Southborough MA, US
Daniel J. Lee - Brookline MA, US
Jennifer Lewis - Cambridge MA, US
John Rosowski - Arlington MA, US
David Kolesky - Cambridge MA, US
Alexander D. Valentine - Windham NH, US

International Classification:

A61F 2/18
A61L 27/54
A61L 27/38
A61L 27/26

Abstract:

This disclosure features artificial tympanic membrane graft devices and two-component bilayer graft devices that include a scaffold having a plurality of ribs made of a first material and a plurality of spaces between the ribs filled or made with the first material, a different, second material, a combination of the first and a second materials, or a combination of a second material and one or more other different materials. The bilayer graft devices have two components or layers. One component, e.g., the under-lay graft device, can include a projection, and the second component, e.g., the overlay graft device, can include an opening that corresponds to the projection (or vice versa) so that the opening and the projection can secure the two layers together in a “lock and key” manner. This disclosure also features methods of making, using, and implanting the three-dimensional artificial tympanic membrane and bilayer graft devices.