- Austin TX, US Ning Lu - Houston TX, US Laura Bover - Pearland TX, US Naoya Tsurushita - Palo Alto CA, US J. Yun Tso - Menlo Park CA, US Shankar Kumar - Pleasanton CA, US
Assignee:
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM - Austin TX
International Classification:
C07K 16/18
US Classification:
4241721, 5303898, 5303873
Abstract:
Anti-human sema4A antibodies useful in treating autoimmune diseases, cancers and other disease are provided herein. Anti-human sema4A antibodies can inhibit T cell proliferation and Th2 differentiation induced by IL-4, anti-CD3, anti-CD28 and recombinant sema4A.