Noah Malmstadt from 3314 Alicia Ave, Altadena, CA 91001, age 49

Formation And Encapsulation Of Molecular Bilayer And Monolayer Membranes
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US Patent:

8038885, Oct 18, 2011
Filed:

Oct 13, 2006
Appl. No.:

12/083410
Inventors:

Jacob J. Schmidt - Sherman Oaks CA, US
Noah Malmstadt - Pasadena CA, US
Tae-joon Jeon - Los Angeles CA, US
Jason Poulos - Los Angeles CA, US
Assignee:

The Regents of the University of California - Oakland CA
International Classification:

B01D 11/00
G01N 1/18
US Classification:

210639, 264 41, 264 46, 264 47, 427 211, 427 214, 435 4, 435 71, 4352871, 4352872, 4352873, 436 86, 436178, 436180, 977713, 977717, 977756
Abstract:

Disclosed herein are compositions, methods, and devices related to bilayer and monolayer membranes, their encapsulation in a hydrogel, and their formation. Methods of using the disclose compositions and devices are also disclosed.

Stimuli-Responsive Polymer Conjugates And Related Methods
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US Patent:

20060127925, Jun 15, 2006
Filed:

Aug 3, 2005
Appl. No.:

11/197771
Inventors:

Patrick Stayton - Seattle WA, US
Allan Hoffman - Seattle WA, US
Noah Malmstadt - Pasadena CA, US
Tsuyoshi Shimoboji - Nagaizumi, JP
Samarth Kulkarni - Seattle WA, US
Assignee:

University of Washington - Seattle WA
International Classification:

C12Q 1/68
G01N 33/53
C12M 1/34
B05D 3/02
US Classification:

435006000, 435007100, 427002110, 435287200
Abstract:

Conjugates that include polymers that are reversibly self-associative in response to a stimulus and methods for using the conjugates.

Formation And Encapsulation Of Molecular Bilayer And Monolayer Membranes
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US Patent:

20120025414, Feb 2, 2012
Filed:

Oct 7, 2011
Appl. No.:

13/269433
Inventors:

Jacob J. Schmidt - Sherman Oaks CA, US
Noah Malmstadt - Pasadena CA, US
Tae-joon Jeon - Los Angeles CA, US
Jason Poulos - Los Angeles CA, US
International Classification:

B29D 7/01
B29C 31/10
B82Y 40/00
US Classification:

264212, 425130, 977962
Abstract:

Disclosed herein are compositions, methods, and devices related to bilayer and monolayer membranes, their encapsulation in a hydrogel, and their formation. Methods of using the disclosed compositions and devices are also disclosed.

Continuous Flow Synthesis Of Nanomaterials Using Ionic Liquids In Microfluidic Reactors
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US Patent:

20130087020, Apr 11, 2013
Filed:

Oct 8, 2012
Appl. No.:

13/647242
Inventors:

University of Southern California - Los Angeles CA, US
Noah Malmstadt - Altadena CA, US
Laura Lazarus - Long Beach CA, US
Astro S.-J. Yang - Los Angeles CA, US
Carson Riche - Zionsville PA, US
Steven Chu - Honolulu HI, US
Brandon Marin - West Covina CA, US
Assignee:

UNIVERSITY OF SOUTHERN CALIFORNIA - Los Angeles CA
International Classification:

B22F 9/18
US Classification:

75370
Abstract:

A method for manufacturing metal nanoparticles includes the use of a microfluidic device. The microfluidic device has a first channel having a first inlet; a second channel having a second inlet; a third channel having a third inlet; and a main channel having a main inlet and an outlet. The first channel, second channel, and third channel all lead into the main channel. The method involves injecting a solution of a metal/ligand into the first inlet, injecting a solution of a reducing agent into the second inlet, injecting a solvent comprised of an ionic liquid into the third inlet, and injecting an inert carrier into the main inlet. The solution of the metal/ligand, the solution of the reducing agent, the solvent and the inert carrier are combined together in the main channel, and the metal/ligand and the reducing agent are reacted for a time sufficient to form a metal nanoparticle.

Microfluidic Devices Having Solvent-Resistant Coating And Method Of Manufacture Thereof
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US Patent:

20140030165, Jan 30, 2014
Filed:

Jul 26, 2013
Appl. No.:

13/951990
Inventors:

Carson Riche - Zionsville PA, US
Noah Malmstadt - Altadena CA, US
Brandon Marin - West Covina CA, US
Malancha Gupta - Pasadena CA, US
Assignee:

UNIVERSITY OF SOUTHERN CALIFORNIA - Los Angeles CA
International Classification:

B01L 3/00
US Classification:

422502, 42725539, 427237
Abstract:

A method of coating a substrate, such as a microfluidic device having an interior surface, includes heating a gas including a perfluoroacrylate, a crosslinker and an initiator at a first temperature, maintaining the substrate at a second temperature lower than the first temperature in a reaction chamber, exposing the heated gas to the substrate in the reaction chamber, and reacting the perfluoroacrylate with the initiator and crosslinker to form a polymer coating on the surface of the substrate.

Discrete Elements For 3D Microfluidics
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US Patent:

20190270083, Sep 5, 2019
Filed:

Nov 13, 2018
Appl. No.:

16/189133
Inventors:

- Los Angeles CA, US
- Mountain View CA, US
Noah Malmstadt - Altadena CA, US
International Classification:

B01L 3/00
Abstract:

A module may be provided with at least one opening, the opening being an endpoint of a microfluidic channel that passes through at least part of the module. A set of multiple such modules may be arranged into an arrangement of modules, which may be coupled together using one or more coupling mechanisms included on each module. The arrangement of modules may fit within a regular polyhedral grid, and each module within the arrangement of modules may have a form suitable for arrangement of the modules within the regular polyhedral grid. Fluid may then flow through at least a subset of the arrangement of modules via the microfluidic channel of each module of the subset of the arrangement of modules. Some modules may include sensors, actuators, or inner microfluidic channel surface coatings. The arrangement of modules may form a microfluidic circuit that can perform a microfluidic circuit function.

G Protein-Coupled Receptors Incorporated Into Rehydrated Polymer Vesicles Retain Functionality
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US Patent:

20180177729, Jun 28, 2018
Filed:

Dec 27, 2017
Appl. No.:

15/855353
Inventors:

- LOS ANGELES CA, US
NOAH MALMSTADT - LOS ANGELES CA, US
CARSON RICHE - ZIONSVILLE PA, US
International Classification:

A61K 9/127
A61K 47/42
Abstract:

A G Protein Coupled Receptor (GPCR) is incorporated in polymeric giant unilamellar protein vesicles (pGUPs). By utilizing an agarose rehydration technique, the GPCR is inserted in the biased, physiological orientation with the C-terminus cytosolic and N-terminus extracellular. The GPCR is fully functional within the polymeric bilayer, exhibiting physiological responses to various ligands. The entire population of GPCRs in pGUPs remains fully functional after lyophilization for 120 hours.

Discrete Elements For 3D Microfluidics
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US Patent:

20150352550, Dec 10, 2015
Filed:

Jun 10, 2015
Appl. No.:

14/735941
Inventors:

- Los Angeles CA, US
- Mountain View CA, US
Noah Malmstadt - Altadena CA, US
Assignee:

REOLAB INC. - Mountain View CA
UNIVERSITY OF SOUTHERN CALIFORNIA - Los Angeles CA
International Classification:

B01L 3/00
Abstract:

A module may be provided with at least one opening, the opening being an endpoint of a microfluidic channel that passes through at least part of the module. A set of multiple such modules may be arranged into an arrangement of modules, which may be coupled together using one or more coupling mechanisms included on each module. The arrangement of modules may fit within a regular polyhedral grid, and each module within the arrangement of modules may have a form suitable for arrangement of the modules within the regular polyhedral grid. Fluid may then flow through at least a subset of the arrangement of modules via the microfluidic channel of each module of the subset of the arrangement of modules. Some modules may include sensors, actuators, or inner microfluidic channel surface coatings. The arrangement of modules may form a microfluidic circuit that can perform a microfluidic circuit function.