Norman David Nelson

US Patent:

7767447, Aug 3, 2010

Filed:

Dec 12, 2008

Appl. No.:

12/333484

Inventors:

Scott S. Breidenthal - Oceanside CA, US
Sara H. Fan - San Diego CA, US
Richard S. Lee - San Diego CA, US
Norman C. Nelson - San Diego CA, US
Michael S. Poirier - Vista CA, US
Matthew J. Scott - Oceanside CA, US
Jason A. Taylor - Windham NH, US

Assignee:

Gen-Probe Incorporated - San Diego CA
Qualigen, Inc. - Carlsbad CA

International Classification:

C12M 1/00
C12M 3/00

US Classification:

4353031, 435 6, 4352861, 4352871, 4352872

Abstract:

A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte present in a sample. The detector can be used to detect an optical signal emitted by the contents of the receptacle.

US Patent:

7780336, Aug 24, 2010

Filed:

Dec 12, 2008

Appl. No.:

12/333482

Inventors:

Scott S. Breidenthal - Oceanside CA, US
Sara H. Fan - San Diego CA, US
Richard S. Lee - San Diego CA, US
Norman C. Nelson - San Diego CA, US
Matthew J. Scott - Oceanside CA, US
Jason A. Taylor - Windham NH, US

Assignee:

Gen-Probe Incorporated - San Diego CA
Qualigen, Inc. - Carlsbad CA

International Classification:

B01F 11/00
B01F 15/06
G01N 35/00
B01L 3/00

US Classification:

366142, 366143, 366144, 422 681, 436172

Abstract:

A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte present in a sample. The detector can be used to detect an optical signal emitted by the contents of the receptacle.

US Patent:

8048375, Nov 1, 2011

Filed:

Dec 12, 2008

Appl. No.:

12/333335

Inventors:

Scott S. Breidenthal - Oceanside CA, US
Richard S. Lee - San Diego CA, US
Norman C. Nelson - San Diego CA, US
Matthew J. Scott - Oceanside CA, US
Jason A. Taylor - Windham NH, US
Sara H. Fan - San Diego CA, US

Assignee:

Gen-Probe Incorporated - San Diego CA
Qualigen, Inc. - Carlsbad CA

International Classification:

G01N 15/06

US Classification:

422 681, 366142, 366143, 436172

Abstract:

A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector.

US Patent:

8052929, Nov 8, 2011

Filed:

Apr 1, 2011

Appl. No.:

13/078348

Inventors:

Scott S. Breidenthal - Oceanside CA, US
Sara H. Fan - San Diego CA, US
Richard S. Lee - San Diego CA, US
Norman C. Nelson - San Diego CA, US
Matthew J. Scott - Oceanside CA, US
Jason A. Taylor - Windham NH, US

Assignee:

Gen-Probe Incorporated - San Diego CA
Qualigen, Inc. - Carlsbad CA

International Classification:

G01N 15/06

US Classification:

422 681, 366142, 366143, 436172

Abstract:

A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector.

US Patent:

8221705, Jul 17, 2012

Filed:

Dec 17, 2008

Appl. No.:

12/337108

Inventors:

Scott S. Breidenthal - Oceanside CA, US
Daniel L. Kacian - San Diego CA, US
Richard S. Lee - San Diego CA, US
Norman C. Nelson - San Diego CA, US
Matthew J. Scott - Oceanside CA, US
Jason A. Taylor - Windham NH, US

Assignee:

Gen-Probe, Incorporated - San Diego CA

International Classification:

G01N 33/00

US Classification:

422552, 422547, 422551

Abstract:

A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte present in a sample. The detector can be used to detect an optical signal emitted by the contents of the receptacle.

US Patent:

8480976, Jul 9, 2013

Filed:

Jul 13, 2011

Appl. No.:

13/181850

Inventors:

Scott S. Breidenthal - Oceanside CA, US
Sara H. Fan - San Diego CA, US
Richard S. Lee - San Diego CA, US
Norman C. Nelson - San Diego CA, US
Matthew J. Scott - Oceanside CA, US
Jason A. Taylor - Windham NH, US

Assignee:

Gen-Probe Incorporated - San Diego CA
Qualigen, Inc. - Carlsbad CA

International Classification:

B01L 3/00

US Classification:

422504, 366142, 366143, 366144, 422 681, 436172

Abstract:

A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte present in a sample. The detector can be used to detect an optical signal emitted by the contents of the receptacle.

US Patent:

8491178, Jul 23, 2013

Filed:

Mar 7, 2012

Appl. No.:

13/414195

Inventors:

Scott S. Breidenthal - Oceanside CA, US
Sara H. Fan - San Diego CA, US
Richard S. Lee - San Diego CA, US
Norman C. Nelson - San Diego CA, US
Matthew J. Scott - Oceanside CA, US
Jason A. Taylor - Windham NH, US

Assignee:

Gen-Probe Incorporated - San Diego CA
Qualigen, Inc. - Carlsbad CA

International Classification:

B01F 15/00
B01F 11/00
G01N 21/01

US Classification:

366142, 366143, 366275, 422 8205, 4352887

Abstract:

A receptacle having interconnected chambers arranged to permit multiple process steps to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte present in a sample. The detector can be used to detect an optical signal emitted by the contents of the receptacle.

US Patent:

20090136963, May 28, 2009

Filed:

Dec 12, 2008

Appl. No.:

12/333455

Inventors:

Scott S. Breidenthal - Oceanside CA, US
Sara H. Fan - San Diego CA, US
Richard S. Lee - San Diego CA, US
Norman C. Nelson - San Diego CA, US
Matthew J. Scott - Oceanside CA, US
Jason A. Taylor - Windham NH, US

Assignee:

GEN-PROBE INCORPORATED - San Diego CA
QUALIGEN, INC. - Carlsbad CA

International Classification:

C12Q 1/68
G01N 1/18
G01N 33/00

US Classification:

435 6, 436178, 436 94

Abstract:

A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte present in a sample. The detector can be used to detect an optical signal emitted by the contents of the receptacle.