Pablo Jose Prado

US Patent:

6977503, Dec 20, 2005

Filed:

Feb 10, 2003

Appl. No.:

10/361410

Inventors:

Pablo J. Prado - San Diego CA, US

Assignee:

Quantum Magnetics, Inc. - San Diego CA

International Classification:

G01V003/00

US Classification:

324319, 324320

Abstract:

A magnetic resonance imaging apparatus and method having a magnet assembly, which provides substantially flat surfaces of constant magnetic field outside the assembly and a set of magnetic field gradients. One-, two-, and three-dimensional images are rendered. The static magnetic field is virtually uniform within horizontal degrees of freedom and decreases monotonically in a direction away from the surface. An RF probe, for example, a coil, located adjacent the surface, produces a field substantially perpendicular to the static magnetic field. A magnetic field gradient is set to horizontally scan a given level within the sensitive volume. Received magnetic resonance signals are detected by the coil for a depth corresponding to the excitation frequency. As the tuning and excitation frequency is switched to lower values, signals are generated for layers progressively farther from the surface. The RF probe is automatically tuned.

US Patent:

7759938, Jul 20, 2010

Filed:

Dec 28, 2007

Appl. No.:

11/966331

Inventors:

Pablo J. Prado - San Diego CA, US
Sankaran Kumar - San Marcos CA, US
Erik Edmund Magnuson - Cardiff CA, US

Assignee:

Morpho Detection, Inc. - Newark CA

International Classification:

G01V 3/00

US Classification:

324319, 324320, 335296

Abstract:

Apparatus and method for varying field strength in a magnetic resonance system while keeping a relatively uniform magnetic field distribution. In an embodiment, a two-pole, generally u-shaped magnet assembly generates a static and uniform magnetic field. The magnet assembly includes two facing magnet poles separated by an air gap. Holes may be formed with the magnet poles. The field control rods may be placed at a pre-determined distance into these holes and symmetrically or asymmetrically moved across each magnet poles in a controlled manner to change the magnetic field strength while keeping the uniform magnetic field distribution. Maximum magnetic field strength may occur when the rods are removed. Minimum magnetic field strength may occur when the rods are fully inserted.

US Patent:

D669181, Oct 16, 2012

Filed:

Aug 13, 2010

Appl. No.:

29/367800

Inventors:

Pablo Prado - Boston MA, US

International Classification:

2401

US Classification:

D24158

US Patent:

D669182, Oct 16, 2012

Filed:

Aug 13, 2010

Appl. No.:

29/367802

Inventors:

Pablo Prado - Boston MA, US

International Classification:

2401

US Classification:

D24158

US Patent:

8519708, Aug 27, 2013

Filed:

Nov 6, 2008

Appl. No.:

12/741789

Inventors:

Pablo J. Prado - Boston MA, US

Assignee:

T2 Biosystems, Inc. - Lexington MA

International Classification:

G01V 3/00

US Classification:

324309

Abstract:

Small and inexpensive probeheads for use in nuclear magnetic resonance systems, in particular, magnetic resonance relaxometry systems are provided. The design of the magnet-radiofrequency coil configurations within the probeheads is guided by an excitation bandwidth associated with radiofrequency pulses to be applied to a sample.

US Patent:

20020084783, Jul 4, 2002

Filed:

Dec 18, 2001

Appl. No.:

10/026067

Inventors:

Bernhard Blumich - Roetgen, DE
Michael Bruder - Hamburg, DE
Thomas Guerlin - Neustadt, DE
Pablo Prado - San Diego CA, US

International Classification:

G01V003/00

US Classification:

324/322000, 324/309000, 324/318000, 324/307000

Abstract:

In an apparatus for examining flat goods of polymeric material having reinforcement structures embedded therein, a number of NMR-MOUSE probes are provided on a measuring surface of an examining body for nuclear magnetic resonance imaging analysis of the flat goods.

US Patent:

20020089330, Jul 11, 2002

Filed:

Feb 19, 2002

Appl. No.:

10/078069

Inventors:

Bernhard Blumich - Roetgen, DE
Michael Bruder - Hamburg, DE
Thomas Guerlin - Neustadt, DE
Pablo Prado - San Diego CA, US

International Classification:

G01V003/00

US Classification:

324/322000, 324/318000, 324/309000, 324/307000

Abstract:

In an apparatus for examining flat goods of polymeric material having reinforcement structures embedded therein, a number of NMR-MOUSE probes are provided on a measuring surface of an examining body for nuclear magnetic resonance imaging analysis of the flat goods.

US Patent:

20120223705, Sep 6, 2012

Filed:

Dec 19, 2008

Appl. No.:

12/809424

Inventors:

Thomas J. Lowery - Belmont MA, US
Pablo J. Prado - Boston MA, US

Assignee:

T2 Biosystems, Inc. - Cambridge MA

International Classification:

G01R 33/44

US Classification:

324307

Abstract:

Nuclear magnetic resonance systems and methods of use thereof are provided. The systems employ implantable radiofrequency coils () and optionally implantable magnets (). The systems can employ weak permanent magnets and/or permanent magnets that provide magnetic fields that are much less homogeneous than in conventional systems. This allows, for example, for inexpensive and simple probeheads for nuclear magnetic resonance relaxometry with suitable biosensors. The methods of the present invention allow in-vivo magnetic resonance measurements and, in particular, monitoring of analytes and determination of medical diagnostic information, for example, based on determined magnetic resonance parameters.