Paige T Anderson

US Patent:

20060078898, Apr 13, 2006

Filed:

Oct 12, 2004

Appl. No.:

10/964504

Inventors:

Bo Curry - Redwood City CA, US
Paige Anderson - Belmont CA, US

International Classification:

C12Q 1/68
C07H 21/04

US Classification:

435006000, 536024300

Abstract:

Methods and compositions for performing array-based CGH assays are provided. In general, the methods involve evaluating copy number of a genomic region by evaluating binding of distinguishably labeled populations of nucleic acids to a first CGH array in which: a) the populations of nucleic acids are labeled by a labeled primer and/or b) binding is assessed relative to binding of dye-swapped populations of nucleic acids to a second CGH array. Kits and systems for use in practicing the subject methods are also provided.

US Patent:

20060078899, Apr 13, 2006

Filed:

Oct 12, 2004

Appl. No.:

10/964505

Inventors:

Alicia Scheffer - Redwood City CA, US
Paige Anderson - Belmont CA, US
Diane Ilsley - San Jose CA, US
Michael Barrett - Mountain View CA, US
Bo Curry - Redwood City CA, US

International Classification:

C12Q 1/68
C12P 19/34

US Classification:

435006000, 435091200

Abstract:

Methods and compositions for producing a labeled population of nucleic acids for use in an array-based comparative genome hybridization (CGH) assay are provided. In general, the methods involve cleaving a genomic source to produce a sample containing nucleic acid fragments, and end-labeling the nucleic acid fragments to provide a population of nucleic acids having a terminal label. Kits and systems for use in practicing the subject methods are also provided.

US Patent:

20060172316, Aug 3, 2006

Filed:

Jan 31, 2005

Appl. No.:

11/048152

Inventors:

Paige Anderson - Redwood City CA, US
Samar Lightfoot - San Francisco CA, US

International Classification:

C12Q 1/68
G06F 19/00
C12P 19/34

US Classification:

435006000, 435091200, 702020000

Abstract:

A method of assessing the quality of an amplified nucleic acid sample is described. The method includes (a) separating the amplified nucleic acid sample to obtain a separation profile; (b) determining a first component of said separation profile corresponding to a first nucleic acid fraction; (c) determining a second component of said separation profile corresponding to a second nucleic acid fraction; and (d) assigning a quality value to the amplified nucleic acid sample based on the first component and the second component.

US Patent:

20210317442, Oct 14, 2021

Filed:

Jun 2, 2021

Appl. No.:

17/337186

Inventors:

- Santa Clara CA, US
Paige Anderson - Belmont CA, US
Javelin Chi - Sunnyvale CA, US
Henrik Johansson - Mountain View CA, US

International Classification:

C12N 15/10
C12Q 1/6848
C12Q 1/6874
C12Q 1/6806
C12Q 1/689
A63F 13/55

Abstract:

The present invention relates to nucleic acid samples for massively parallel sequencing. More particularly, the present invention relates to assay methods, compositions and kits for detecting contamination of nucleic acid identifiers such as sample barcodes.

US Patent:

20200181602, Jun 11, 2020

Filed:

Feb 17, 2020

Appl. No.:

16/792813

Inventors:

- Santa Clara CA, US
Paige Anderson - Belmont CA, US
Javelin Chi - Sunnyvale CA, US
Henrik Johansson - Mountain View CA, US

International Classification:

C12N 15/10
C12Q 1/6874
C12Q 1/6848
C12Q 1/689
C12Q 1/6806

Abstract:

The present invention relates to nucleic acid samples for massively parallel sequencing. More particularly, the present invention relates to assay methods, compositions and kits for detecting contamination of nucleic acid identifiers such as sample barcodes.

US Patent:

20190010488, Jan 10, 2019

Filed:

Jul 10, 2017

Appl. No.:

15/645085

Inventors:

- Santa Clara CA, US
Paige Anderson - Mountain View CA, US
Javelin Chi - Sunnyvale CA, US
Henrik Johansson - Stockholm, SE

International Classification:

C12N 15/10
C12Q 1/68

Abstract:

The present invention relates to nucleic acid samples for massively parallel sequencing. More particularly, the present invention relates to assay methods, compositions and kits for detecting contamination of nucleic acid identifiers such as sample barcodes.

US Patent:

20180135115, May 17, 2018

Filed:

Nov 14, 2016

Appl. No.:

15/351312

Inventors:

- Santa Clara CA, US
Paige Anderson - Mountain View CA, US

International Classification:

C12Q 1/68

Abstract:

Provided herein, among other things, are compositions for improving signal-to-noise in hybridization to oligonucleotide arrays. In some embodiments, the composition may comprise a population of indexing oligonucleotides of formula X-Y, where the sequences of region X hybridize to an array and the sequences of region Y hybridize to distinct sites within a genomic region, transcript, set of transcripts, or complement of the same. Use of these oligonucleotides increases signal, reduces background and smoothens array hybridization analyses. Methods and kits that employ the compositions are also provided.

US Patent:

20150361422, Dec 17, 2015

Filed:

Nov 21, 2014

Appl. No.:

14/550713

Inventors:

- Loveland CO, US
Nicholas M. Sampas - San Jose CA, US
Joel Myerson - Berkeley CA, US
Paige Anderson - Belmont CA, US
Bo Curry - Redwood City CA, US

International Classification:

C12N 15/10
B01J 19/00

Abstract:

Provided herein, among other things, is a method comprising: (a) obtaining a mixture of multiple sets of oligonucleotides, wherein the oligonucleotides within each set each comprise a terminal indexer sequence can be assembled to produce a synthon; and (b) hybridizing the oligonucleotide mixture to an array, thereby spatially-separating the different sets of oligonucleotides from one another. Other embodiments are also provided.