Paige N Anderson

US Patent:

62943669, Sep 25, 2001

Filed:

Aug 19, 1998

Appl. No.:

9/136574

Inventors:

Graham K. Farrington - Acton MA
Paige Anderson - Medford MA
Peter Bergquist - Chatswood, AU
Roy Daniels - Hamilton, NZ
Moreland David Gibbs - Lane Cove, AU
Hugh Morgan - Hamilton, NZ
Diane P. Williams - Hopkinton MA

Assignee:

Clariant Finance (BVI) Limited - Tortola

International Classification:

C12N 942

US Classification:

435209

Abstract:

Alkalophilic and thermophilic cellulases having high stability to elevated temperatures and pH have been isolated from an organism of unknown species, which most closely resembles those in the Caldicellulosiruptor genus and which has been called by us, Tok7B. 1, These cellulases have been cloned and expressed in a recombinant system, so that they can be produced in quantity. These are particularly useful in treating cellulosic materials including cotton-containing fabrics, as detergent additives, and in aqueous compositions. We also provide genomic DNA which can be used in recombinant expression vectors and expression systems to produce enhanced alkali and/or temperature stability properties in cellulases other than those specifically described.