Pao T Lin

US Patent:

20210364442, Nov 25, 2021

Filed:

May 19, 2021

Appl. No.:

17/325109

Inventors:

- College Station TX, US
Pao Tai Lin - College Station TX, US

International Classification:

G01N 21/65
G01J 3/44

Abstract:

Raman spectroscopy of chemical and biological samples can be accomplished with photonic sensors amenable to chip-scale integration. In various embodiments, such a photonic sensor includes first and second optical waveguides coupled via an optical ring resonator, the ring resonator configured to resonantly enhance, and selectively couple into the second optical waveguide, a Raman scattering signal generated, when the first waveguide and/or resonator are exposed to a sample, by interaction of an analyte in the sample with excitation light coupled into the first optical waveguide.

US Patent:

20210364510, Nov 25, 2021

Filed:

May 19, 2021

Appl. No.:

17/324851

Inventors:

- College Station TX, US
Pao Tai Lin - College Station TX, US

International Classification:

G01N 33/543
G02B 6/10
G01N 33/569

Abstract:

A photonic biosensor including a biological probe disposed on a mid-infrared-transparent waveguide can be used to detect biological analytes in biological samples, using specific binding of the analyte to the probe in conjunction with absorption spectroscopy. In various embodiments, the biosensor is used for molecular diagnostics, e.g., to detect oligonucleotides or proteins associated with a coronavirus.

US Patent:

20200103344, Apr 2, 2020

Filed:

Oct 1, 2019

Appl. No.:

16/589818

Inventors:

- College Station TX, US
Pao Tai Lin - College Station TX, US

International Classification:

G01N 21/59
G01N 33/00

Abstract:

Chalcogenide waveguides with high width-to-height aspect ratios and a smooth exposed surfaces can serve as mid-infrared evanescent-absorption-based sensors for detecting and identifying volatile organic compounds and/or determining their concentration, optionally in real-time. The waveguide sensors may be manufactured using a modified sputtering process in which the sputtering target and waveguide substrate are titled and/or laterally offset relative to each other and the substrate is continuously rotated.

US Patent:

20190187061, Jun 20, 2019

Filed:

Dec 7, 2018

Appl. No.:

16/213376

Inventors:

- Cambridge MA, US
Jianwei MU - Pleasanton CA, US
Anuradha Murthy AGARWAL - Weston MA, US
Pao Tai LIN - Brighton MA, US
Lionel Cooper KIMERLING - Concord MA, US

International Classification:

G01N 21/77
G01N 21/64
G01N 21/65
G01N 21/41
G01N 33/543

Abstract:

A sensing apparatus includes a light source to transmit a light beam, an input switch, a first sensing element, a second sensing element, and a detector. The input switch receives the light beam and includes a phase change material having a first state and a second state. The first sensing element receives the light beam from the input switch when the phase change material is in the first state and produces a first change in the light beam in response to a presence of a first analyte. The second sensing element receives the light beam from the input switch when the phase change material is in the second state and produces a second change in the light beam in response to a presence of a second analyte. The detector detects the first change and/or the second change in the light beam.

US Patent:

20190128798, May 2, 2019

Filed:

Nov 2, 2018

Appl. No.:

16/179502

Inventors:

Pao Tai Lin - College Station TX, US

International Classification:

G01N 21/25
G02B 6/10
G01N 21/3504
G01N 21/3577

Abstract:

A flexible waveguide structure including a waveguide on a flexible substrate, both having transparent windows in the mid-infrared range, may serve as a photonic chemical sensor for measuring characteristic absorptions of analytes brought in physical contact with the waveguide. Such a sensor may, in accordance with some embodiments, be formed by an aluminum-nitride waveguide on a borosilicate substrate.

US Patent:

20190129094, May 2, 2019

Filed:

Nov 2, 2018

Appl. No.:

16/179470

Inventors:

Pao Tai Lin - College Station TX, US

International Classification:

G02B 6/10
G01N 21/35
G01N 21/25

Abstract:

A waveguide structure including a mid-infrared-transparent waveguide on a mid-infrared-transparent undercladding may serve as a photonic chemical sensor for measuring characteristic absorptions of analytes brought in physical contact with the waveguide. In some embodiments, a sensor including an amorphous-silicon waveguide on a barium-titanate undercladding can operate at wavelengths ranging from 2.5 μm to about 7 μm; this sensor may be manufactured by epitaxial growth of the undercladding on a substrate, followed by CMOS-compatible creation of the waveguide. Additional embodiments are disclosed.

US Patent:

20180070868, Mar 15, 2018

Filed:

Sep 12, 2017

Appl. No.:

15/702114

Inventors:

- College Station TX, US
Pao T. Lin - College Station TX, US

Assignee:

The Texas A&M University System - College Station TX

International Classification:

A61B 5/1455
G02B 6/122
G01J 3/28
A61B 5/145

Abstract:

An apparatus for detecting an analyte, and method of operating and forming the same. In one embodiment, the apparatus includes a pedestal formed on a semiconductor substrate and a mid-infrared (“IR”) transparent semiconductor waveguide formed on the pedestal. A refractive index of the pedestal is less than the mid-IR transparent semiconductor waveguide. The apparatus also includes a detector configured to detect an analyte couplable to the mid-IR transparent semiconductor waveguide.

US Patent:

20180024072, Jan 25, 2018

Filed:

Feb 6, 2017

Appl. No.:

15/425443

Inventors:

Zhaohong HAN - Cambridge MA, US
Jianwei MU - Quincy MA, US
Anuradha Murthy AGARWAL - Weston MA, US
Pao Tai LIN - Brighton MA, US
Lionel Cooper KIMERLING - Concord MA, US

International Classification:

G01N 21/77
G01N 33/543

Abstract:

A sensing apparatus includes a light source to transmit a light beam, an input switch, a first sensing element, a second sensing element, and a detector. The input switch receives the light beam and includes a phase change material having a first state and a second state. The first sensing element receives the light beam from the input switch when the phase change material is in the first state and produces a first change in the light beam in response to a presence of a first analyte. The second sensing element receives the light beam from the input switch when the phase change material is in the second state and produces a second change in the light beam in response to a presence of a second analyte. The detector detects the first change and/or the second change in the light beam.