Patrick J Dowd

US Patent:

8334366, Dec 18, 2012

Filed:

Apr 29, 2010

Appl. No.:

12/770343

Inventors:

Stephen R. Hughes - Peoria IL, US
Patrick F. Dowd - Peoria IL, US

Assignee:

The United States of America, as represented by the Secretary of Agriculture - Washington DC

International Classification:

C07K 14/00
C07H 21/02
C12N 15/00

US Classification:

530350, 536 231, 4353201

Abstract:

Lycotoxin-1 peptide mutant peptides which exhibit increased insecticidal activity are produced by substitution of both a proline for the lysine at amino acid position 24 and a tryptophan for the leucine at amino acid position 25 of the wild-type amino acid sequence for lycotoxin-1. Further substitution of amino acids 8, 9 or 10 of the lycotoxin-1 wild-type amino acid sequence, specifically substituting a histidine for the phenylalanine at amino acid position 8, a glutamine for the glycine at amino acid position 10, or a serine for the leucine at amino acid position 9, provides an even greater increase in insecticidal activity. In addition to changes in the lycotoxin-1 amino acid sequence, the addition of an enterokinase K recognition site, DDDK, to the N-terminus of the lycotoxin-1 peptide increases insecticidal activity further still. Isolated nucleic acid sequences encoding the mutant lycotoxin-1 peptides, expression vectors containing these sequences, microorganisms or other host cells transformed with these vectors, and recombinant methods for producing the peptides, are also disclosed.

US Patent:

50817884, Jan 21, 1992

Filed:

May 1, 1991

Appl. No.:

7/694534

Inventors:

Patrick F. Dowd - Peoria IL
Robert J. Bartelt - East Peoria IL
Donald T. Wicklow - Peoria IL

Assignee:

The United States of America as represented by the Secretary of
Agriculture - Washington DC

International Classification:

A01M 104

US Classification:

43107

Abstract:

An insect trap for attracting and capturing flying insects. The apparatus includes a chamber for holding an insect attractant and exposing the same to a current of air, and having a first opening allowing passage of air but not insects therein. Positioned opposite the first opening, at least one funnel-shaped entrance to the chamber allows entry of the insects into the trap, as well as passage of air currents and entrained attractant odors out of the trap. An insect collection container, optionally having a one-way entrance, is also provided, and communicates with the chamber through a second chamber opening and the one-way entrance. Proper orientation of the trap in the wind is achieved by mounting a wind vane or fins onto the exterior of the chamber so as to position the first opening upwind, and the funnel-shaped entrance to the chamber downwind from the first opening. In the alternative, the wind vane may be omitted and the chamber constructed in the shape of a wedge, tapering toward the first opening, to enable trap orientation in like manner.

US Patent:

50116835, Apr 30, 1991

Filed:

Nov 25, 1988

Appl. No.:

7/275863

Inventors:

Robert J. Bartelt - East Peoria IL
Patrick F. Dowd - Peoria IL

Assignee:

The United States of America as represented by the Secretary of
Agriculture - Washington DC

International Classification:

A07N 2500
A07N 2700
C07C 900

US Classification:

424 84

Abstract:

A male-produced aggregation pheromone was demonstrated in Carpophilus hemipterus (L. ) (Coleoptera: Nitidulidae) using a wind-tunnel bioassay. The attractiveness of the pheromone is greatly enhanced by volatiles from a host plant, and combinations of pheromone and food volatiles typically attract 3-10 times more beetles than either source by itself. The pheromone consists of a series of 13-, 14-, and 15-carbon unsaturated hydrocarbons, the most abundant of which is 3,5,7-trimethyl-(E,E,E,E)-2,4,6,8-decatetraene.

US Patent:

54525403, Sep 26, 1995

Filed:

Dec 17, 1993

Appl. No.:

8/169806

Inventors:

Patrick F. Dowd - Peoria IL
Fernando E. Vega - Peoria IL

Assignee:

The United States of America as represented by the Secretary of
Agriculture - Washington DC

International Classification:

A01M 120

US Classification:

43107

Abstract:

A device for use with a funnel drop-type trap for autoinoculation of active agents with insects. The device comprises a collecting chamber, an entrance near the top of the chamber for entry of the insects from the trap and for direction of the insects to the agent positioned on the surface below the entrance. At least one exit for escape of the insects is located on the sidewall of the chamber.

US Patent:

50084780, Apr 16, 1991

Filed:

Jul 31, 1989

Appl. No.:

7/387555

Inventors:

Robert J. Bartelt - East Peoria IL
Patrick F. Dowd - Peoria IL

Assignee:

The United States of America as represented by the Secretary of
Agriculture - Washington DC

International Classification:

C07C 900

US Classification:

585 16

Abstract:

Male-produced aggregation pheromones were demonstrated in Carpophilus hemipterus (L. ), Carpophilus lugubris Murray, and Carpophilus freemani Dobson (Coleoptera: Nitidulidae) using a wind-tunnel bioassay. The attractiveness of the pheromones is greatly enhanced by volatiles from a host plant, and combinations of pheromone and food volatiles typically attract 3-10 times more beetles than either source by itself. The pheromones consist of a series of 12-, 13-, 14-, and 15-carbon unsaturated hydrocarbons. The most abundant of these in C. hemipterus is (2E,4E,6E,8E)-3,5,7-trimethyl-2,4,6,8-decatetraene. In C. lugubris, the most abundant is (2E,4E,6E,8E)-7-ethyl-3,5-dimethyl-2,4,6,8-undecatetraene, and in C. freemani, (2E,4E,6E)-5-ethyl-3-methyl-2,4,6-nonatriene.

US Patent:

55190529, May 21, 1996

Filed:

Jul 29, 1994

Appl. No.:

8/283034

Inventors:

Patrick F. Dowd - Peoria IL
James B. Gloer - Iowa City IA
Donald T. Wicklow - Peoria IL

Assignee:

The United States of America as represented by the Secretary of
Agriculture - Washington DC
University of Iowa Research Foundation and Biotechnology Research and
Development Corp. - Peoria IL

International Classification:

A01N 4308
A01N 4316
C07D30746
C07D31100

US Classification:

514455

Abstract:

Carbonarins A, B, C, D, E, F, G, and H have been isolated from the sclerotia of the fungus Aspergillus carbonarius. The carbonarins are effective for controlling Coleopteran and Lepidopteran insects. The carbonarins have the structure: ##STR1## wherein: R. sub. 1 is a hydrogen atom or a hydroxy group; R. sub. 2 is a hydrogen atom or a methoxy group; R. sub. 3 is a hydrogen atom or a naphthopyrone group; and X is an oxygen atom or an NH group.

US Patent:

50175980, May 21, 1991

Filed:

May 17, 1989

Appl. No.:

7/353363

Inventors:

Patrick F. Dowd - Peoria IL
Donald T. Wicklow - Peoria IL
James B. Gloer - Iowa City IA
Brad L. Rinderknecht - Long Beach CA

Assignee:

The United States of America, as represented by the Secretary of
Agriculture - Washington DC
University of Iowa Research Foundation - Iowa City IA

International Classification:

A61K 3140
C07D20912

US Classification:

514415

Abstract:

A novel indole diterpene compound named "nominine" has been isolated from the sclerotia of the fungus, Aspergillus nomius. Nominine is characterized by the structural formula ##STR1## and is effective for controlling Lepidopteran and Coleopteran insect pests.

US Patent:

49563530, Sep 11, 1990

Filed:

Jun 16, 1988

Appl. No.:

7/207589

Inventors:

Patrick F. Dowd - Peoria IL

Assignee:

The United States of America as represented by the Secretary of
Agriculture - Washington DC

International Classification:

A01N 3506
A01N 3718
A01N 4308
A01N 4316

US Classification:

514 65

Abstract:

Kojic acid and its esters have been found to be more effective synergists for pyrethroid and carbamate insecticides on H. zea and S. frugiperda. Thus they may serve as replacements for the widely used methylene dioxyphenyl compounds such as piperonyl butoxide.