Patrick R Pinson

US Patent:

7943777, May 17, 2011

Filed:

Oct 5, 2009

Appl. No.:

12/573809

Inventors:

Jolene Bradford - Eugene OR, US
Ching-Ying Cheung - San Ramon CA, US
Shih-Jung Huang - Eugene OR, US
Patrick Pinson - Eugene OR, US
Stephen Yue - Eugene OR, US

Assignee:

Life Technologies Corporation - Carlsbad CA

International Classification:

C07D 417/00
C07D 215/00
C07D 251/38

US Classification:

548159, 546153, 546159

Abstract:

Chemical compounds having a high selectivity for double stranded DNA over RNA and single stranded DNA are disclosed. The chemical compounds are stains that become fluorescent upon illumination and interaction with double stranded DNA, but exhibit reduced or no fluorescence in the absence of double stranded DNA. The compounds can be used in a variety of biological applications to qualitatively or quantitatively assay DNA, even in the presence of RNA.

US Patent:

20060263844, Nov 23, 2006

Filed:

May 11, 2006

Appl. No.:

11/432814

Inventors:

Jolene Bradford - Eugene OR, US
Ching-Ying Cheung - San Ramon CA, US
Shih-Jung Huang - Eugene OR, US
Patrick Pinson - Eugene OR, US
Stephen Yue - Eugene OR, US

International Classification:

C12Q 1/02

US Classification:

435029000

Abstract:

Chemical compounds having a high selectivity for double stranded DNA over RNA and single stranded DNA are disclosed. The chemical compounds are stains that become fluorescent upon illumination and interaction with double stranded DNA, but exhibit reduced or no fluorescence in the absence of double stranded DNA. The compounds can be used in a variety of biological applications to qualitatively or quantitatively assay DNA, even in the presence of RNA.

US Patent:

20110217699, Sep 8, 2011

Filed:

May 10, 2011

Appl. No.:

13/104413

Inventors:

Jolene A. Bradford - Eugene OR, US
Ching-Ying Cheung - San Ramon CA, US
Shih Jung Huang - Eugene OR, US
Patrick R. Pinson - Eugene OR, US
Stephen T. Yue - Eugene OR, US

Assignee:

LIFE TECHNOLOGIES CORPORATION - Carlsbad CA

International Classification:

C12Q 1/68
C07D 417/06
C07D 417/14

US Classification:

435 61, 546157, 546176, 546163, 546162, 544363

Abstract:

Chemical compounds having a high selectivity for double stranded DNA over RNA and single stranded DNA are disclosed. The chemical compounds are stains that become fluorescent upon illumination and interaction with double stranded DNA, but exhibit reduced or no fluorescence in the absence of double stranded DNA. The compounds can be used in a variety of biological applications to qualitatively or quantitatively assay DNA, even in the presence of RNA.

US Patent:

20120288855, Nov 15, 2012

Filed:

Jul 26, 2012

Appl. No.:

13/559300

Inventors:

Jolene A. Bradford - Eugene OR, US
Ching-Ying Cheung - San Ramon CA, US
Shih-Jung Huang - Eugene OR, US
Patrick R. Pinson - Eugene OR, US
Stephen T. Yue - Eugene OR, US

Assignee:

LIFE TECHNOLOGIES CORPORATION - Carlsbad CA

International Classification:

G01N 21/76
C07D 417/14
C07D 413/06
C07D 417/06

US Classification:

435 61, 546165, 544363, 546158, 546163, 5462701

Abstract:

Chemical compounds having a high selectivity for double stranded DNA over RNA and single stranded DNA are disclosed. The chemical compounds are stains that become fluorescent upon illumination and interaction with double stranded DNA, but exhibit reduced or no fluorescence in the absence of double stranded DNA. The compounds can be used in a variety of biological applications to qualitatively or quantitatively assay DNA, even in the presence of RNA.

US Patent:

20130224735, Aug 29, 2013

Filed:

Apr 11, 2013

Appl. No.:

13/861123

Inventors:

Life Technologies Corporation - , US
Ching-Ying Cheung - San Ramon CA, US
Shih-Jung Huang - Eugene OR, US
Patrick Pinson - Eugene OR, US
Stephen Yue - Eugene OR, US

Assignee:

Life Technologies Corporation - Carlsbad CA

International Classification:

G01N 21/64

US Classification:

435 61, 546157, 546162, 544363, 544128

Abstract:

Chemical compounds having a high selectivity for double stranded DNA over RNA and single stranded DNA are disclosed. The chemical compounds are stains that become fluorescent upon illumination and interaction with double stranded DNA, but exhibit reduced or no fluorescence in the absence of double stranded DNA. The compounds can be used in a variety of biological applications to qualitatively or quantitatively assay DNA, even in the presence of RNA.

US Patent:

20150316558, Nov 5, 2015

Filed:

Jul 13, 2015

Appl. No.:

14/797415

Inventors:

- Carlsbad CA, US
Ching-Ying CHEUNG - San Ramon CA, US
Shih-Jung HUANG - Eugene OR, US
Patrick PINSON - Eugene OR, US
Stephen YUE - Eugene OR, US

International Classification:

G01N 33/58
C07D 417/06
C07D 417/14
G01N 21/64

Abstract:

Chemical compounds having a high selectivity for double stranded DNA over RNA and single stranded DNA are disclosed. The chemical compounds are stains that become fluorescent upon illumination and interaction with double stranded DNA, but exhibit reduced or no fluorescence in the absence of double stranded DNA. The compounds can be used in a variety of biological applications to qualitatively or quantitatively assay DNA, even in the presence of RNA.

US Patent:

20150004597, Jan 1, 2015

Filed:

Sep 17, 2014

Appl. No.:

14/488751

Inventors:

- Carlsbad CA, US
Ching-Ying CHEUNG - San Ramon CA, US
Shih-Jung HUANG - Eugene OR, US
Patrick PINSON - Eugene OR, US
Stephen YUE - Eugene OR, US

International Classification:

C12Q 1/68
C07D 417/06

US Classification:

435 61, 546163, 544363, 546158, 546165

Abstract:

Chemical compounds having a high selectivity for double stranded DNA over RNA and single stranded DNA are disclosed. The chemical compounds are stains that become fluorescent upon illumination and interaction with double stranded DNA, but exhibit reduced or no fluorescence in the absence of double stranded DNA. The compounds can be used in a variety of biological applications to qualitatively or quantitatively assay DNA, even in the presence of RNA.