Qun Kevin Fang - Wellesley MA, US Frank Xinhe Wu - Shrewsbury MA, US Paul T. Grover - Plainville MA, US Seth C. Hopkins - Clinton MA, US Una Campbell - Marlborough MA, US Milan Chytil - Clinton MA, US Kerry L. Spear - Concord MA, US
Imidazo[1,2-a]pyridines are disclosed. Compounds of the invention are useful therapeutic agents and their inclusion in pharmaceutical formulations and use in methods of treatment are disclosed. Many of the compounds disclosed herein may be represented by the following generic formula:.
Bupropion Metabolites And Methods Of Their Synthesis And Use
Kevin Fang - Wellesley MA, US Chrisantha Senanayake - Shrewsbury MA, US Paul Grover - Franklin MA, US
Assignee:
SEPRACOR INC.
International Classification:
A61K031/724 A61K031/5375 A61K031/138
US Classification:
514/058000, 514/238800, 514/653000
Abstract:
Methods and compositions are disclosed which utilize metabolites of bupropion for treating disorders ameliorated by inhibition of neuronal monoamine reuptake. Such disorders include, but are not limited to, sexual dysfunction, affective disorders, cerebral function disorders, cigarette smoking, and incontinence. Methods of making optically pure bupropion metabolites are also disclosed.
Kevin Fang - Wellesley MA, US Chrisanthia Senanayake - Shrewsbury MA, US Paul Grover - Franklin MA, US
International Classification:
A61K 31/537
US Classification:
514238800
Abstract:
Methods and compositions are disclosed which utilize metabolites of bupropion for treating disorders ameliorated by inhibition of neuronal monoamine reuptake. Such disorders include, but are not limited to, sexual dysfunction, affective disorders, cerebral function disorders, cigarette smoking, and incontinence. Methods of making optically pure bupropion metabolites are also disclosed.
Bupropion Metabolites And Methods Of Their Synthesis And Use
Methods and compositions are disclosed which utilize metabolites of bupropion for treating disorders ameliorated by inhibition of neuronal monoamine reuptake. Such disorders include, but are not limited to, sexual dysfunction, affective disorders, cerebral function disorders, cigarette smoking, and incontinence. Methods of making optically pure bupropion metabolites are also disclosed.
Robert Bruce DIEBOLD - Waltham MA, US Thomas GERO - Waltham MA, US Paul GROVER - Waltham MA, US Shan HUANG - Waltham MA, US Stephanos IOANNIDIS - Waltham MA, US Claude Afona OGOE - Waltham MA, US Jamal Carlos SAEH - Waltham MA, US Jeffrey Gilbert VARNES - Waltham MA, US
The present invention relates to compounds of Formula (I):and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds inhibit Bcl-2 and/or Bcl-Xactivities and may be used for the treatment of cancer.
Robert Bruce Diebold - Waltham MA, US Thomas Gero - Waltham MA, US Paul Grover - Waltham MA, US Shan Huang - Waltham MA, US Stephanos Ioannidis - Waltham MA, US Claude Afona Ogoe - Waltham MA, US Jamal Carlos Saeh - Waltham MA, US Jeffrey Gilbert Varnes - Waltham MA, US
The present invention relates to compounds of Formula (I): and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds inhibit Bcl-2 and/or Bcl-Xactivities and may be used for the treatment of cancer.
Paul Grover / Pool via AP The Duke and Duchess of Cambridge and the Duke and Duchess of Sussex attend a National Service to mark the centenary of the Armistice at Westminster Abbey.
Date: Nov 12, 2018
Category: Headlines
Source: Google
Taylor Swift on serial boyfriends, home buying in Vanity Fair
We ran that by Paul Grover of Robert Paul Properties, which has a handle on the disposition of every significant waterfront parcel on the Cape, and he confirmed that the property has changed hands in the past month or so.
Date: Mar 06, 2013
Category: Entertainment
Source: Google
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Paul Grover
Paul Grover
About:
Former Brighton lad now living in Liverpool - i do though dont i though!
Paul Grover
Paul Grover
Paul Grover
Paul Grover
Paul Grover
Paul Grover
Youtube
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