Peter B Davis

US Patent:

6359061, Mar 19, 2002

Filed:

Mar 19, 1999

Appl. No.:

09/272106

Inventors:

Eric Edward Swayze - Carlsbad CA
Peter William Davis - Encinitas CA

Assignee:

ISIS Pharmaceuticals, Inc. - Carlsbad CA

International Classification:

C07D21172

US Classification:

525 5411, 514579, 546316, 548228, 548229, 5483164, 5483361, 5483381, 5483385, 548477, 548497, 558390, 558430, 558438, 558442, 540148, 540158, 564 1, 564 50, 564105, 544358

Abstract:

Amide compounds of formula (I), combinatorial libraries of amide compounds and methods of preparing the same are provided. Libraries of the invention are useful for screening in biological assays in order to identify pharmaceutically useful compounds.

US Patent:

6448373, Sep 10, 2002

Filed:

Jan 11, 1994

Appl. No.:

08/179970

Inventors:

Phillip D. Cook - Carlsbad CA
Oscar L. Acevedo - San Diego CA
Peter W. Davis - Carlsbad CA
David J. Ecker - Leucadia CA
Normand Herbert - San Marcos CA

Assignee:

ISIS Pharmaceuticals, Inc. - Carlsbad CA

International Classification:

A61K 3800

US Classification:

530300, 435 6, 436501, 514 2, 514 44, 536 221, 530323, 530332, 530333

Abstract:

Novel ethylene glycol compounds bearing various functional groups are used to prepare oligomeric structures. The ethylene glycol monomers can be joined via standard phosphate linkages including phosphodiester and phosphorothioate linkages. Useful functional groups include nucleobases as well as polar groups, hydrophobic groups, ionic groups, aromatic groups and/or groups that participate in hydrogen-bonding.

US Patent:

6558633, May 6, 2003

Filed:

Sep 21, 1994

Appl. No.:

08/309925

Inventors:

David J. Ecker - Leucadia CA
Oscar Acevedo - San Diego CA
Normand Hebert - Cardiff CA
Peter W. Davis - Carlsbad CA
Jacqueline R. Wyatt - Carlsbad CA
John S. Kiely - San Diego CA

Assignee:

ISIS Pharmaceuticals, Inc. - Carlsbad CA

International Classification:

C12M 118

US Classification:

422134, 422 50, 422131, 4352885, 4352884, 4353052

Abstract:

Chemical reaction apparatus, materials and methods are provided for the automatable, efficient synthesis of chemical species and libraries. In accordance with preferred embodiments, chemical droplet generation and direction techniques are employed to prepare oligomers and libraries of chemical species. Reaction assemblies adapted for efficient synthetic employment and for improved collection are also disclosed.

US Patent:

6750344, Jun 15, 2004

Filed:

Sep 5, 1997

Appl. No.:

08/924851

Inventors:

Eric Edward Swayze - Carlsbad CA
Peter William Davis - Encinitas CA
Robert Jay Tinder - La Jolla CA
Kelly G. Sprankle - Vista CA

Assignee:

ISIS Pharmaceuticals, Inc. - Carlsbad CA

International Classification:

C07D24136

US Classification:

544355, 544338, 544336, 544349, 435 4, 435 71, 436501, 436518, 436536

Abstract:

The present invention provides monocyclic, bicyclic and oligomeric amine compounds with at least two sites of diversity. These compounds are formed from monocyclic scaffolds which can be cyclized to form bicyclic amine scaffolds. These can then be reacted with building blocks to form the amine compounds of the invention. This invention further provides libraries or monocyclic, bicyclic and oligomeric amine compounds. Also provided are methods for preparing monocyclic, bicyclic and oligomeric amine compounds and libraries thereof. The present invention also provides pharmaceutical compositions of the monocyclic, bicyclic and oligomeric amine compounds.

US Patent:

7266715, Sep 4, 2007

Filed:

Apr 29, 2003

Appl. No.:

10/425787

Inventors:

John Bazzinotti - Norwood MA, US
Peter Scott Davis - Wakefield MA, US
Timothy Steven Champagne - Attleborough MA, US
Kenneth John Wante - Bellingham MA, US

Assignee:

Cisco Technology, Inc. - San Jose CA

International Classification:

G06F 11/00

US Classification:

714 4, 714 47

Abstract:

A client device establishes a virtual private network connection with a central site or network through a master concentrator. The master concentrator transmits state information, relating to the virtual private network connection, to a backup concentrator. In the event the master concentrator fails during a communications session between the client device and the network, the backup concentrator maintains the communication session between the client device and the network over the virtual private network connection using the connection state information received from the master concentrator. Such a configuration allows for failover of a virtual private network connection from the master concentrator to the backup concentrator without requiring the client device to re-establish the virtual private network connection with the central site or network. The configuration also allows the client device to maintain an existing communications session with the network.

US Patent:

7376743, May 20, 2008

Filed:

Oct 29, 2002

Appl. No.:

10/282816

Inventors:

John Bazzinotti - Norwood MA, US
Peter Scott Davis - Wakefield MA, US
Kenneth John Wante - Bellingham MA, US
Timothy Steven Champagne - South Attleborough MA, US
Dany J. Rochefort - Norfolk MA, US

Assignee:

Cisco Technology, Inc. - San Jose CA

International Classification:

G06F 15/16
G06F 15/177
G06F 15/173
G06F 3/00
G06F 5/00
G06F 11/00
G01R 31/08
G08C 15/00
H04J 1/16
H04J 3/14
H04L 1/00
H04L 12/26

US Classification:

709229, 709220, 709226, 710 38, 370236, 370237

Abstract:

In a virtual private network, a plurality of concentrators form an interface to provide client/remote site access to a private network over a public network. The plurality of concentrators are grouped into a virtual cluster. Each concentrator in the virtual cluster has an IP address and the virtual cluster has a virtual IP address. In operation, one of the plurality of concentrators assumes the virtual IP address and acts as the master device in the cluster. When a client attempts a connection to the private network, the client addresses an initial request to the virtual IP address. The master device responds to the client request by transmitting to the client the IP address of a concentrator in the cluster selected to handle the connection.

US Patent:

7444415, Oct 28, 2008

Filed:

Oct 29, 2002

Appl. No.:

10/282503

Inventors:

John Bazzinotti - Norwood MA, US
Peter Davis - Wakefield MA, US
Victor Volpe - Groton MA, US
Rashmi Pitre - Shrewsbury MA, US
Keith Mader - Raynham MA, US

Assignee:

Cisco Technology, Inc. - San Jose CA

International Classification:

G06F 15/16

US Classification:

709229, 709217, 709218, 709219, 709227, 709245, 709250

Abstract:

A virtual private network device enables individual machines at a remote subnet to be visible and addressable from a central site by establishing a private address range for the remote machines, forming a virtual private network tunnel from the virtual private network device to the central site, and communicating the private address range to the central site to enable connections from the central site to individual machines on the remote subnet.

US Patent:

7624437, Nov 24, 2009

Filed:

May 1, 2002

Appl. No.:

10/136480

Inventors:

Arturo Fagundo - Westborough MA, US
John Bazzinotti - Norwood MA, US
Peter Davis - Wakefield MA, US
Andrew Rodwin - Acton MA, US

Assignee:

Cisco Technology, Inc. - San Jose CA

International Classification:

G06F 15/16

US Classification:

726 15, 726 3, 726 14, 713153

Abstract:

In a hardware client for remote logon to a network, a two layer authentication protocol enables authorized users to log on while discouraging unauthorized users. The hardware client prevents logging on to the network if the hardware client is stolen. The hardware client itself is authenticated in the first authentication layer in order to establish a link to the network. Then a client computer authenticates in a second layer and further establishes a secure connection to the network. If the power of the hardware client goes off (as it would if or example it were unplugged for transport), then the authentication is not saved and therefore is lost. The hardware client must be reauthenticated before it can be used again.