Peter P Yin

US Patent:

20190201900, Jul 4, 2019

Filed:

Feb 25, 2019

Appl. No.:

16/285092

Inventors:

- Los Angeles CA, US
Sam Gurley - South Pasadena CA, US
Aaron Cipriano - Fullerton CA, US
Peter Yin - Culver City CA, US
Rob Purnell - Los Angeles CA, US
Ming Petrullo - Redondo Beach CA, US
Stelica Stelea - Yorba Linda CA, US

Assignee:

Sensor Kinesis Corp. - Los Angeles CA

International Classification:

B01L 3/00

Abstract:

A field portable diagnostic apparatus uses a rotatable disk in which a microfluidic circuit is defined. The microfluidic circuit includes a centrifugal separation chamber receiving a sample to stratify the sample. A magnetic bead holding chamber is communicated to a mixing chamber, where mass amplifying functionalized magnetic-nanoparticles, held in a buffer solution and contained in the magnetic bead holding reservoir communicated to mixing chamber, are mixed with the separated fluid delivered to mixing chamber from the separation chamber. The functionalized magnetic nanoparticles conjugate with a target analyte in the sample. A magnet in proximity to a SAW chamber including a SAW detector draws the functionalized magnetic nanoparticles toward antibodies immobilized on the SAW sensor surface A wash reservoir is communicated to the SAW sensor chamber, and a cleanup/waste reservoir is communicated to the SAW chamber for receive fluid after it has passed through the SAW chamber.

US Patent:

20190030533, Jan 31, 2019

Filed:

Oct 4, 2018

Appl. No.:

16/152029

Inventors:

- Los Angeles CA, US
Sam Gurley - South Pasadena CA, US
Aaron Cipriano - Fullerton CA, US
Peter Yin - Culver City CA, US
Rob Purnell - Los Angeles CA, US
Ming Petrullo - Redondo Beach CA, US
Stelica Stelea - Yorba Linda CA, US
Marlon S. Thomas - Riverside CA, US

Assignee:

Sensor Kinesis Corp. - Los Angeles CA

International Classification:

B01L 3/00
G01N 29/02
G01N 29/036
H03H 9/145

Abstract:

An cartridge is combined with a smart device which is capable of communicating with a network to perform a portable, fast, field assay of a small sample biological analyte. A closed microfluidic circuit for mixes the analyte with a buffer with functionalized magnetic beads capable of being specifically combined with the analyte. A detector communicates with the microfluidic circuit in which the mixed analyte, buffer and combined functionalized magnetic beads are sensed. A microcontroller is coupled to detector for controlling the detector and for data processing an output assay signal from the detector. A user interface communicates with the microcontroller for providing user input and for providing user output through the smart device to the network.