A method and apparatus for detecting a fluorescent substance tagged to a microparticle are described. The device comprises a single capillary flow carrier system for transporting the microparticle past a selected location, a source of electromagnetic radiation for irradiating the substance tagged to the microparticle, and a detection system for measuring fluorescent light emitted from the substance at the selected location. The method comprises transporting the microparticle to a selected location, irradiating a fluorescent substance tagged to the microparticle, and measuring the fluorescent light emitted from the fluorescent substance at the selected location.
Method And Apparatus For Detecting Microparticles In Fluid Samples
A method and apparatus for detecting a fluorescent substance tagged to a microparticle are described. The device comprises a single capillary flow carrier system for transporting the microparticle past a selected location, a source of electromagnetic radiation for irradiating the substance tagged to the microparticle, and a detection system for measuring fluorescent light emitted from the substance at the selected location. The method comprises transporting the microparticle to a selected location, irradiating a fluorescent substance tagged to the microparticle, and measuring the fluorescent light emitted from the fluorescent substance at the selected location.
A particle analyzer in which tagged particles to be analyzed are drawn through a suspended capillary tube where a predetermined volume in the capillary tube is illuminated. The illumination scattered by said particles is detected by a detector to count all particles. The fluorescent illumination emitted by tagged particles is detected and the output signals from the fluorescent detectors and scatter detector are processed to provide an analysis of the particles.
Single Detector Multicolor Particle Analyzer And Method
Philippe Goix - Oakland CA, US Paul J. Lingane - Oakland CA, US
Assignee:
Guava Technologies, Inc. - Hayward CA
International Classification:
G01N 15/06 G01N 21/00 F21V 9/16 C02F 1/40
US Classification:
250573, 2504581, 422 81, 204602
Abstract:
A multicolor particle analyzer and method is described. The particles each of which either naturally fluoresce or are tagged to fluoresce at distinctive wavelengths are caused to flow through an analyzing volume where fluorescence is excited by an impinging light beam. A tunable optical filter repetitively and sequentially passes emitted light at each of the characteristic wavelengths as each particle travels through the analyzing volume and the light transmitted through the optical filter is received by single detector which provides output signals representative of each distinct wavelength of light emitted by the particle.
Method For Highly Sensitive Detection Of Single Protein Molecules Labeled With Fluorescent Moieties
Philippe J. Goix - Oakland CA, US Robert Puskas - Manchester MO, US John Todd - Lafayette CA, US Richard A. Livingston - Webster Groves MO, US Douglas Held - Ballwin MO, US
Assignee:
Singulex, Inc. - Alameda CA
International Classification:
G01N 21/76
US Classification:
436172, 436164
Abstract:
Disclosed are methods, kits, and compositions for the highly sensitive detection of molecules. The methods, kits, and compositions are useful in determining concentrations of molecules in samples to levels of 1 femtomolar, 1 attomolar, or lower. The methods, kits, and compositions also allow the determination of concentration over a wide range, e. g. , 7-log range, without need for sample dilution.
Highly Sensitive System And Methods For Analysis Of Troponin
Philippe J. Goix - Oakland CA, US Robert Puskas - Manchester MO, US John Todd - Lafayette CA, US Richard A. Livingston - Webster Groves MO, US Douglas Held - Ballwin MO, US Alan Wu - Palo Alto CA, US
Assignee:
Singulex, Inc. - Alameda CA The Regents of the University of California - Oakland CA
International Classification:
G01N 33/53
US Classification:
435 71, 435 72, 436518
Abstract:
The invention provides methods, compositions, kits, and systems for the sensitive detection of cardiac troponin. Such methods, compositions, kits, and systems are useful in diagnosis, prognosis, and determination of methods of treatment in conditions that involve release of cardiac troponin.
Philippe J. Goix - Oakland CA, US Paul J. Lingane - Redwood City CA, US Kenneth F. Uffenheimer - Los Gatos CA, US
Assignee:
Millipore Corporation - Billerica MA
International Classification:
G01N 33/00
US Classification:
422 73, 422 681, 422 63, 422 50
Abstract:
A particle analyzer in which tagged particles to be analyzed are drawn through a suspended capillary tube where a predetermined volume in the capillary tube is illuminated. The illumination scattered by said particles is detected by a detector to count all particles. The fluorescent illumination emitted by tagged particles is detected and the output signals from the fluorescent detectors and scatter detector are processed to provide an analysis of the particles.
Philippe J. Goix - Oakland CA, US Paul J. Lingane - Redwood City CA, US Kenneth F. Uffenheimer - Los Gatos CA, US
Assignee:
EMD Millipore Corporation - Billerica MA
International Classification:
G01N 33/00
US Classification:
422 73, 422 681, 422 63, 422 50
Abstract:
A particle analyzer in which tagged particles to be analyzed are drawn through a suspended capillary tube where a predetermined volume in the capillary tube is illuminated. The illumination scattered by said particles is detected by a detector to count all particles. The fluorescent illumination emitted by tagged particles is detected and the output signals from the fluorescent detectors and scatter detector are processed to provide an analysis of the particles.
Name / Title
Company / Classification
Phones & Addresses
Philippe Goix Chief Exec, President, Chief Executive Offi
1701 Hbr Bay Pkwy SUITE 200, Alameda, CA 94502 1650 Hbr Pkwy, Alameda, CA 94502 1650 Hbr Bay Pkwy, Alameda, CA 94502 1701 Hbr Bay Pkwy 200, Alameda, CA 94502 (510)8149000, (510)9959092
Matrix Medical Fitness and Spa
Owner and General Manager
Eon Medical Wellness
Owner
Sourceenergetix
Co-Founder and Chief Executive Officer
Avant Diagnostics Mar 2017 - Dec 2017
President and Chief Executive Officer
Prismhealthdx Oct 2015 - Mar 2017
Chairman and Chief Executive Officer
Education:
University of San Francisco 1993 - 1995
Master of Business Administration, Masters, Marketing, Finance
University of Rouen France 1984 - 1987
Doctorates, Doctor of Philosophy, Physics, Philosophy
University of Rouen France 1983 - 1984
Master of Science, Masters, Physics
University of Rouen France 1980 - 1983
Bachelors, Bachelor of Science, Mechanical Engineering
University of Rouen, France
Doctorates, Doctor of Philosophy, Physics, Philosophy
Skills:
Biotechnology R&D Start Ups Product Development Strategic Planning Life Sciences Pharmaceutical Industry Drug Discovery Marketing Strategy Oncology Marketing Microsoft Office Budgets Commercialization of High Valued Products In Life Sciences and Healthcare Powerpoint Public Speaking Photoshop Social Media Investments