Pravin R Patel

US Patent:

6833139, Dec 21, 2004

Filed:

Jan 9, 2002

Appl. No.:

10/042818

Inventors:

Mark Lemko - Plymouth MI
Pravin M. Patel - Bloomfield Hills MI

Assignee:

Ferndale Laboratories, Inc. - Ferndale MI

International Classification:

A61K 9127

US Classification:

424450, 514882

Abstract:

A topical preparation for the treatment of anorectal disorders comprises L arginine and a local anesthetic. The L arginine typically comprises 0. 1-5% by weight of the composition, and the local anesthetic typically comprises, by weight, 1-15% of the composition. Lidocaine is particularly preferred local anesthetic. In some embodiments, the composition includes a liposomal carrier, and the local anesthetic is encapsulated within the liposomes.

US Patent:

7378405, May 27, 2008

Filed:

Jan 22, 2004

Appl. No.:

10/762652

Inventors:

Pravin M. Patel - Bloomfield Hills MI, US

Assignee:

Triax Pharmaceuticals, LLC - Cranford NJ

International Classification:

A61K 31/56

US Classification:

514180, 514181

Abstract:

Stabilized 17-substituted hydrocortisone containing compositions and methods of manufacture. Isomerization of the hydrocortisone component of topical steroid compositions is markedly reduced by introducing an omega-6. acid in the form of linoleic acid into the skin preparation. Preferably, the linoleic acid is added as a component of refined safflower oil. The omega-6 acid has been found to be an effective way of preventing the isomerization of hydrocortisone 17-butyrate into the undesirable isomer HC21-B.

US Patent:

7476400, Jan 13, 2009

Filed:

Nov 8, 2002

Appl. No.:

10/290983

Inventors:

Pravin M. Patel - Bloomfield Hills MI, US

Assignee:

Ferndale IP, Inc. - Ferndale MI

International Classification:

A61K 9/127

US Classification:

424450, 424489

Abstract:

A composition comprising lidocaine-containing liposomes wherein the weight concentration of lidocaine in said composition is greater than 10%. The composition is prepared by mixing water with an oil phase comprising lidocaine, a C-Calcohol, an alkyl ester of a fatty acid, propylene glycol, and a polyalkyl stearate. The non-aqueous phase may also include a phospholipid such as phosphatidyl choline.

US Patent:

7981877, Jul 19, 2011

Filed:

May 11, 2006

Appl. No.:

11/432742

Inventors:

Pravin M. Patel - Bloomfield Hills MI, US

International Classification:

A61K 31/56

US Classification:

514182

Abstract:

Stabilized, 17-substituted hydrocortisone containing compositions and methods of manufacture are disclosed. Isomerization of the hydrocortisone component of topical steroid compositions is markedly reduced by including an omega-6 acid component in the form of a free acid or as a compound such as an ester. Specifically disclosed are methods for preventing the isomerization of hydrocortisone 17-butyrate into hydrocortisone 21-butyrate through the use of safflower oil.

US Patent:

20030215493, Nov 20, 2003

Filed:

Apr 30, 2003

Appl. No.:

10/425359

Inventors:

Pravin Patel - Bloomfield Hills MI, US

International Classification:

A61K009/127
A61K031/203

US Classification:

424/450000, 514/559000

Abstract:

A topical composition for the treatment of acne and other dermatological conditions comprises a liposomal formulation of a retinoid and an antibiotic in which the retinoid is disposed in the lipid phase of the formulation, and the antibiotic is disposed in the aqueous phase. Lincosamides, such as clindamycin, are one group of antibiotics which may be used in the composition. Tretinoin is one preferred retinoid. Also disclosed are methods for making the compositions and methods for using the composition.

US Patent:

20090148511, Jun 11, 2009

Filed:

Feb 16, 2009

Appl. No.:

12/371783

Inventors:

Pravin M. Patel - Bloomfield Hills MI, US

International Classification:

A61K 9/127
A61P 17/00

US Classification:

424450

Abstract:

A topical composition for the treatment of acne and other dermatological conditions comprises a liposomal formulation of a retinoid and an antibiotic in which the retinoid is disposed in the lipid phase of the formulation, and the antibiotic is disposed in the aqueous phase. Lincosamides, such as clindamycin, are one group of antibiotics which may be used in the composition. Tretinoin is one preferred retinoid. Also disclosed are methods for making the compositions and methods for using the composition.

US Patent:

20100286108, Nov 11, 2010

Filed:

Jul 21, 2010

Appl. No.:

12/840487

Inventors:

Pravin M. Patel - Bloomfield Hills MI, US

International Classification:

A61K 31/56
A61P 29/00

US Classification:

514179

Abstract:

Stabilized, 17-substituted hydrocortisone containing compositions and methods of manufacture are disclosed. Isomerization of the hydrocortisone component of topical steroid compositions is markedly reduced by including an omega-6 acid component in the form of a free acid or as a compound such as an ester. Specifically disclosed are methods for preventing the isomerization of hydrocortisone 17-butyrate into hydrocortisone 21-butyrate through the use of safflower oil.

US Patent:

20110142922, Jun 16, 2011

Filed:

Feb 25, 2011

Appl. No.:

13/035403

Inventors:

Pravin M. Patel - West Bloomfield MI, US

Assignee:

Ferndale IP, Inc. - Ferndale MI

International Classification:

A61K 9/127
A61P 17/10
A61K 31/7056

US Classification:

424450, 514 24

Abstract:

A stabilized, topical composition for the treatment of acne and other dermatological conditions comprises a liposomal formulation of a retinoid and an antibiotic in which the retinoid is disposed in the lipid phase of the formulation, and the antibiotic is disposed in the aqueous phase so as to be isolated from the retinoid. Lincosamides, such as clindamycin, are one group of antibiotics which may be used in the composition. Tretinoin is one preferred retinoid. Also disclosed are methods for making the compositions and methods for using the composition.