Qian Wang

US Patent:

52460045, Sep 21, 1993

Filed:

Aug 14, 1992

Appl. No.:

7/929941

Inventors:

Richard H. Clarke - Big Sky MT
Qian Wang - Boston MA

Assignee:

Angiomedics II, Inc. - Newton MA

International Classification:

A61B 0506

US Classification:

128633

Abstract:

Systems and methods for non-invasive blood analysis are disclosed in which blood is illuminated at a plurality of discrete wavelengths selected from the near infrared spectrum. Measurements of the intensity of reflected or transmitted light at such wavelengths are taken, and an analysis of reflectance or transmittance ratios for various wavelengths is performed. Changes in the ratios can be correlated with specific material properties, such as the concentration of cholesterol in a subject's circulatory system.

US Patent:

52224961, Jun 29, 1993

Filed:

Aug 14, 1992

Appl. No.:

7/930141

Inventors:

Richard H. Clarke - Big Sky MT
Qian Wang - Boston MA

Assignee:

Angiomedics II, Inc. - Newton MA

International Classification:

A61B 500

US Classification:

128633

Abstract:

Systems and methods for non-invasive blood analysis for the presence of glucose are disclosed in which blood is illuminated at a plurality of discrete wavelengths selected from the near infrared spectrum. Measurements of the intensity of transmitted or reflected light at such wavelengths are taken, and an analysis of transmittance or reflectance ratios for various wavelengths is performed. Changes in the ratios can be correlated with specific near infrared (IR) absorption peak for glucose at about 1600 nm +/-15 nm which varies with concentration of the analyte (the data wavelength) and the a second (reference) wavelength being sufficiently removed from the first so that measurements of light absorption at this second wavelength are relatively insensitive to the concentration of the analyte and yet the second wavelength is sufficiently close to the first wavelength to minimize interference from scattering effects and the like. Typically, the window bracketing these closely spaced wavelengths will be less than about 300 nm and preferably less than about 60 nm wide and, in some instances, more preferably less than about 30 nm wide.

US Patent:

52224953, Jun 29, 1993

Filed:

Aug 14, 1992

Appl. No.:

7/930070

Inventors:

Richard H. Clarke - Big Sky MT
Qian Wang - Boston MA

Assignee:

Angiomedics II, Inc. - Newton MA

International Classification:

A01B 500

US Classification:

128633

Abstract:

Systems and methods for non-invasive blood analysis are disclosed in which blood is illuminated at a plurality of discrete wavelengths selected from the near infrared spectrum. Measurements of the intensity of transmitted or reflected light at such wavelengths are taken, and an analysis of transmittance or reflectance ratios for various wavelengths is performed. Changes in the ratios can be correlated with specific near infrared (IR) absorption peak for the analyte which varies with concentration of the analyte (the data wavelength) and the a second (reference) wavelength being sufficiently removed from the first so that measurements of light absorption at this second wavelength are relatively insensitive to the concentration of the analyte and yet the second wavelength is sufficiently close to the first wavelength to minimize interference from scattering effects and the like. Typically, the window bracketing these closely spaced wavelengths will be less than about 300 nm and preferably less than about 60 nm wide and, in some instances, more preferably less than about 30 nm wide.