Qiang Chen

US Patent:

6689265, Feb 10, 2004

Filed:

Mar 23, 2001

Appl. No.:

09/815747

Inventors:

Adam Heller - Austin TX
Gregg L. Kenausis - Austin TX
Qiang Chen - Austin TX
Mark S. Vreeke - Alameda CA

Assignee:

TheraSense, Inc. - Alameda CA

International Classification:

G01N 27327

US Classification:

20440309, 20440304, 20440314

Abstract:

A sensor for the detection and measurement of an analyte in a biofluid. The sensor includes two enzymes. One type of sensor measures the concentration of hydrogen peroxide using a thermostable peroxidase enzyme that is immobilized in a redox hydrogel to form a sensing layer on a working electrode. This sensor also includes a hydrogen peroxide-generating second enzyme which is insulated from the redox hydrogel and electrode. This second enzyme generates hydrogen peroxide in response to the presence of an analyte or analyte-generated compound. The second enzyme may be insulated from the electrode by placement of an electrically insulating layer between the sensing layer and the second enzyme layer. Alternatively, the second enzyme is immobilized in an inorganic polymeric matrix, preferably made using a sol-gel polymerization process. Such matrices include those made of silica.

Address:

600 University Oaks Blvd APT M, College Station, TX 77840

Phone:

(979)6931211

VIN:

2G1WT58K379233691

Make:

CHEVROLET

Model:

IMPALA

Year:

2007