Qin Wang

US Patent:

20180010156, Jan 11, 2018

Filed:

Jul 14, 2017

Appl. No.:

15/650265

Inventors:

- Albany NY, US
Ryan C. Tappel - Syracuse NY, US
Qin Wang - Syracuse NY, US

International Classification:

C12P 7/62
C12N 9/88
C12N 9/10

Abstract:

Methods and systems for producing prescribed unit size poly(3-hydroxyalkanoate) (PHA) polymers and copolymers are provided. The methods and systems can employ recombinant bacteria that are not native producers of PHA or lack enzymes to degrade PHA once synthesized, metabolize short to long chain fatty acids without induction, and express an (R)-specific enoyl-CoA hydratase and a PHA synthase, the (R)-specific enoyl-CoA hydratase and PHA synthase having wide substrate specificities. The recombinant bacteria are fed at least one fatty acid substrate that is equal in carbon length to the prescribed or desired unit size of the PHA polymer to be produced. The prescribed unit size PHA that is produced is then isolated and/or purified.

US Patent:

20140349353, Nov 27, 2014

Filed:

Jan 9, 2013

Appl. No.:

14/371025

Inventors:

- Albany NY, US
Ryan C. Tappel - Syracuse NY, US
Qin Wang - Syracuse NY, US

Assignee:

The Research Foundation for the State University of New York - Albany NY

International Classification:

C12P 7/62

US Classification:

435135, 43525233

Abstract:

Methods and systems for producing prescribed unit size poly(3-hydroxyalkanoate) (PHA) polymers and copolymers are provided. The methods and systems can employ recombinant bacteria that are not native producers of PHA or lack enzymes to degrade PHA once synthesized, metabolize short to long chain fatty acids without induction, and express an (R)-specific enoyl-CoA hydratase and a PHA synthase, the (R)-specific enoyl-CoA hydratase and PHA synthase having wide substrate specificities. The recombinant bacteria are fed at least one fatty acid substrate that is equal in carbon length to the prescribed or desired unit size of the PHA polymer to be produced. The prescribed unit size PHA that is produced is then isolated and/or purified.

Address:

3620 Mystic Vly Pkwy, Medford, MA 02155

Phone:

(315)5758340

VIN:

2C4RC1BG6CR292651

Make:

CHRYSLER

Model:

TOWN AND COUNTRY

Year:

2012