Qing M Yang

US Patent:

20220298584, Sep 22, 2022

Filed:

May 13, 2022

Appl. No.:

17/744536

Inventors:

- Denver CO, US
Robin DOWELL - Boulder CO, US
Qing YANG - Longmont CO, US
Nicholas R. MEYERSON - Broomfield CO, US

International Classification:

C12Q 1/6888
G16H 50/20
G16B 25/10
G16H 10/40

Abstract:

The inventive technology includes novel systems, method and compositions for the identification and classification of host-derived RNA biomarkers produced in response to an infection.

US Patent:

20220259682, Aug 18, 2022

Filed:

Mar 3, 2022

Appl. No.:

17/686387

Inventors:

- Denver CO, US
Nicholas R. Meyerson - Broomfield CO, US
Camile L. Paige - Westminster CO, US
Qing Yang - Longmont CO, US
Robin Dowell - Broomfield CO, US

International Classification:

C12Q 1/70
C12Q 1/6804

Abstract:

The current inventive technology is directed to systems, methods, and compositions detection of host signatures of pathogenic infection, and in particular a rapid detection assay configured to detect target RNA transcripts that may be biomarkers of infection. In one embodiment, the invention includes systems, methods and compositions for the early detection of pathogens or infection in an asymptomatic subject through a novel lateral flow assay, which in a preferred embodiment may include a rapid self-administered test strip configured to detect one or more RNA transcript biomarkers produced by a subject's innate immune system in response to a pathogen or infection and present in saliva.

US Patent:

20200319275, Oct 8, 2020

Filed:

Apr 8, 2020

Appl. No.:

16/843681

Inventors:

- Minneapolis MN, US
- University Park PA, US
Xiao-Hong Zhu - Minneapolis MN, US
Hannes M. Wiesner - Minneapolis MN, US
Michael T. Lanagan - University Park PA, US
Qing X. Yang - University Park PA, US
Sebastian Rupprecht - University Park PA, US
Navid P. Gandji - University Park PA, US
Maryam Sarkarat - University Park PA, US

International Classification:

G01R 33/34
G01R 33/54

Abstract:

An apparatus for transmitting and receiving radiofrequency (RF) signals in a magnetic resonance imaging system for proton and X-nuclear imaging includes at least one radiofrequency (RF) coil and an ultrahigh dielectric constant material incorporated within the at least one RF coil. The permittivity of the ultrahigh dielectric constant material depends on a temperature of the material and is tunable. The apparatus also includes a temperature controller that is thermally coupled to the ultrahigh dielectric constant material. The temperature controller is configured to control a temperature of the ultrahigh dielectric constant material to tune and optimize the permittivity of the ultrahigh dielectric constant material. A chemical structure and composition of the ultrahigh dielectric constant material is selected to control and optimize the permittivity and a dielectric loss of the ultrahigh dielectric constant material and a temperature dependence of the ultrahigh dielectric constant material. The apparatus provides denoising effect, high RF coil transmission and reception efficiencies, and improved signal-to-noise ratio for magnetic resonance or spectroscopic imaging applications and has a potential to advance clinical imaging for diagnosis.