William T. Donofrio - Andover MN, US Jeffrey H. Nycz - Collierville TN, US Sarah Anne Audet - Shoreview MN, US Can Cinbis - Shoreview MN, US Michael A. Schugt - St. Paul MN, US Gerard J. Hill - Champlin MN, US Qingshan (Sam) Ye - Plymouth MN, US
Assignee:
Medtronic, Inc. - Minneapolis MA Warsaw Orthodpedic, Inc. - Warsaw IN
An implantable pedometer for measuring the amount of joint use is disclosed. The implantable pedometer includes a sensor adapted for detecting indicators of joint usage. A counter is configured for storing count data corresponding to the number of indicators detected by the sensor and a telemetry circuit is configured for transmitting the count data outside of the body.
Devices and methods for measuring a target ion concentration uses an electrode pair. The pair includes a working electrode and a reference electrode. The working and reference electrodes are ion-selective electrodes (ISEs). The reference ISE can include a sodium ISE. The ISE pair interacts with body fluids where a target ion concentration changes more than sodium ion concentration over time. Some ISE membranes of a pair vary essentially only in the ionophore. An ISE pair can determine the ratio of a target ion concentration to sodium ion concentration in vivo. Periodic measurement of sodium concentration in drawn blood can be used to calibrate an ISE pair and provide target ion concentration as an output. Or, a potassium/sodium ISE pair beneficially monitors potassium concentration changes over time in heart- or kidney-failure patients. Then, manual or automatic titration of a diuretic material can be implemented to maintain a desired potassium concentration.
James K. Carney - Brooklyn Park MN, US Michael A. Schugt - Saint Paul MN, US Qingshan Ye - Plymouth MN, US Can Cinbis - Shoreview MN, US
Assignee:
Medtronic, Inc. - Minneapolis MN
International Classification:
A61N 1/08
US Classification:
607116, 607 37
Abstract:
A medical device for implantation within a patient comprising a lead body including a conductor within the lead body and a transducer supported by the lead body. The conductor is electrically coupled to the transducer by a conductive fluid, paste or gel. The conductive fluid, paste or gel may be contained within a well in the lead body. The transducer may be a MEMS chip and/or an integrated circuit and may perform any of a variety of functions such as sensing physiological data.
Wei Qin - Plymouth MN, US Daniel S. Cheek - Plymouth MN, US Christopher Hobot - Brooklyn Park MN, US Kelvin Bonnema - Brooklyn Park MN, US Randy Meyer - Brooklyn Center MN, US Douglas Dean Nippoldt - Centerville MN, US Vitally G. Sitko - Medina MN, US Qingshan (Sam) Ye - Brooklyn Park MN, US Narayanan Ramamurthy - Alpharetta GA, US
Assignee:
Medtronic, Inc. - Minneapolis MN
International Classification:
G01N 27/333
US Classification:
20440301, 204411, 204416, 205792
Abstract:
Methods and devices for point of care determination of heparin concentration in blood are described. Cartridges including protamine ion sensitive electrodes (ISEs) and reference electrodes and systems for automatically determining heparin concentration in the cartridges are provided. Some systems add blood to a protamine bolus sufficient to bind all heparin, leaving excess protamine. The excess protamine concentration can be determined by measuring the initial slope of the electrode potential rate of change, and comparing the slope to known protamine concentration slope values In some cartridges, an oscillating pressure source moves the blood-protamine mixture back and forth across the protamine ISE. Some systems also use a second blood sample having the heparin removed or degraded to create a blank reference sample. Protamine ISEs can include polyurethane polymer, DNNS ionophore, and NPOE plasticizer.
Capacitor And Inductor Elements Physically Disposed In Series Whose Lumped Parameters Are Electrically Connected In Parallel To Form A Bandstop Filter
Robert Shawn Johnson - North Tonawanda NY, US Kishore Kumar Kondabatni - Williamsville NY, US Christopher Michael Williams - Lancaster NY, US Ryan Thomas Bauer - Plymouth MN, US Scott Brainard - Columbia Heights MN, US Qingshan Ye - Plymouth MN, US Warren S. Dabney - Orchard Park NY, US Robert A. Stevenson - Canyon Country CA, US Jeff Fleigle - Brooklyn Park MN, US Holly Noelle Moschiano - Lancaster NY, US
Assignee:
Greatbatch Ltd. - Clarence NY
International Classification:
A61N 1/00
US Classification:
607 2
Abstract:
One or more inductors and one or more capacitors are physically disposed relative to one another in series and are electrically connected to one another in parallel to form a bandstop filter. Chip inductors and chip capacitors having spaced apart conductive terminals are physically arranged in end-to-end abutting relation to minimize electrical potential between adjacent conductive terminals. The bandstop filter may be hermetically sealed within a biocompatible container for use with an implantable lead or electrode of a medical device. The values of the inductors and the capacitors are selected such that the bandstop filter is resonant at one or more selected frequencies, such as an MRI pulsed frequency.
Devices and methods for measuring a target ion concentration uses an electrode pair. The pair includes a working electrode and a reference electrode. The working and reference electrodes are ion-selective electrodes (ISEs). The reference ISE can include a sodium ISE. The ISE pair interacts with body fluids where a target ion concentration changes more than sodium ion concentration over time. Some ISE membranes of a pair vary essentially only in the ionophore. An ISE pair can determine the ratio of a target ion concentration to sodium ion concentration in vivo. Periodic measurement of sodium concentration in drawn blood can be used to calibrate an ISE pair and provide target ion concentration as an output. Or, a potassium/sodium ISE pair beneficially monitors potassium concentration changes over time in heart- or kidney-failure patients. Then, manual or automatic titration of a diuretic material can be implemented to maintain a desired potassium concentration.
Capacitor And Inductor Elements Physically Disposed In Series Whose Lumped Parameters Are Electrically Connected In Parallel To Form A Bandstop Filter
Robert Shawn Johnson - North Tonawand NY, US Kishore Kumar Kondabatni - Williamsville NY, US Christopher Michael Williams - Lancaster NY, US Ryan Thomas Bauer - Plymouth MN, US Scott Brainard - Columbia Heights MN, US Qingshan Ye - Plymouth MN, US Warren S. Dabney - Orchard Park NY, US Robert A. Stevenson - Canyon Country CA, US Jeff Fleigle - Brooklyn Park MN, US Holly Noell Moschiano - Lancaster NY, US
Assignee:
Greatbatch Ltd. - Clarence NY
International Classification:
A61N 1/00
US Classification:
607 2
Abstract:
One or more inductors and one or more capacitors are physically disposed relative to one another in series and are electrically connected to one another in parallel to form a bandstop filter. Chip inductors and chip capacitors having spaced apart conductive terminals are physically arranged in end-to-end abutting relation to minimize electrical potential between adjacent conductive terminals. The bandstop filter may be hermetically sealed within a biocompatible container for use with an implantable lead or electrode of a medical device. The values of the inductors and the capacitors are selected such that the bandstop filter is resonant at one or more selected frequencies, such as an MRI pulsed frequency.
Biodegradable Shroud For A Dilator/Sheath Assembly
Mark C. Kraus - Independence MN, US Qingshan Ye - Plymouth MN, US
Assignee:
Greatbatch Ltd. - Clarence NY
International Classification:
A61M 5/178
US Classification:
60416403
Abstract:
An introducer assembly includes a sheath and a dilator. A biodegradable shroud covers the distal portion of the introducer assembly on the surface of both the sheath and the dilator. The biodegradable shroud dissolves in blood after being exposed for a predetermined time. Afterwards, the dilator can be separated from the sheath without breaking the sheath. The shroud improves movement of the introducer assembly through a venous system by preventing body tissue from getting caught in the space between the dilator and the shroud, for example should a “fish mouth” separation occur between them.