Qiuhong Q He

US Patent:

20120274323, Nov 1, 2012

Filed:

Apr 15, 2011

Appl. No.:

13/501000

Inventors:

Qiuhong He - Wexford PA, US

Assignee:

University of Pittsburgh - Of the Commonwealth System of Higher Education - Pittsburgh PA

International Classification:

G01R 33/485

US Classification:

324309

Abstract:

Systems and methods employing spin editing techniques to improve magnetic resonance spectroscopy (MRS) and magnetic resonance spectroscopic imaging (MRSI) are discussed. Using these spin editing techniques, magnetic resonance signals of one or more unwanted chemicals (that is, chemicals whose signals are to be filtered out or suppressed) chemicals can be suppressed, so that the signal(s) of a first set of chemicals can be obtained without signals from the one or more unwanted chemicals. Information about and differences between the molecular topologies of the first set of chemicals and the one or more unwanted chemicals can be used to design a sequence that suppresses the one or more unwanted chemicals while allowing acquisition of signal(s) from the first set of chemicals.

US Patent:

20090118611, May 7, 2009

Filed:

Nov 6, 2008

Appl. No.:

12/266007

Inventors:

Qiuhong He - Wexford PA, US

Assignee:

University of Pittsburgh - of the Common Wealth System of Higher Education - Pittsburgh PA

International Classification:

G01R 33/32
A61B 5/055

US Classification:

600422, 324322

Abstract:

System(s) and method(s) for magnetic resonance imaging and spectroscopy, and magnetic resonance spectroscopic imaging (MRSI) are provided. A unified heteronuclear coil system includes a volume coil tuned to detect a first nuclei and a butterfly coil tuned to detect a second nuclei for simultaneous detection of both the first nuclei and the second nuclei signals from human breast tissue and perform MRIS. First nuclei and second nuclei each include H, C, P, Na, and F. The heteronuclear coil system affords detection of NMR-detectable chemicals specific to cancerous breast tissue to improve breast cancer diagnostic specificity. Adjustment of the heteronuclear coil system to detect various nuclei, combined with a specific pulse excitation sequence, facilitates chemical analysis that provides for chemical discrimination and characterization of compounds present in cancerous and other breast tissue as well as healthy breast physiology.

US Patent:

20160154077, Jun 2, 2016

Filed:

Feb 2, 2016

Appl. No.:

15/013584

Inventors:

Qiuhong He - Wexford PA, US

Assignee:

University of Pittsburgh - Of the Commonwealth System of Higher Education - Pittsburgh PA

International Classification:

G01R 33/46
G01R 33/56
G01R 33/34
G01R 33/48

Abstract:

Systems and methods employing spin editing techniques to improve magnetic resonance spectroscopy (MRS) and magnetic resonance spectroscopic imaging (MRSI) are discussed. Using these spin editing techniques, magnetic resonance signals of one or more unwanted chemicals (that is, chemicals whose signals are to be filtered out or suppressed) chemicals can be suppressed, so that the signal(s) of a first set of chemicals can be obtained without signals from the one or more unwanted chemicals. Information about and differences between the molecular topologies of the first set of chemicals and the one or more unwanted chemicals can be used to design a sequence that suppresses the one or more unwanted chemicals while allowing acquisition of signal(s) from the first set of chemicals.

US Patent:

20140296695, Oct 2, 2014

Filed:

Apr 9, 2012

Appl. No.:

14/004624

Inventors:

Qiuhong He - Wexford PA, US

Assignee:

UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION - Pittsburgh PA

International Classification:

G01R 33/485
A61B 5/00
A61B 5/055

US Classification:

600410, 324318

Abstract:

Systems and methods employing spin editing techniques to improve magnetic resonance spectroscopy (MRS) and magnetic resonance spectroscopic imaging (MRSI) are discussed. Using these spin editing techniques, magnetic resonance signals of one or more non-target chemicals (chemicals whose signals are to be filtered out or suppressed) chemicals can be suppressed, so that the signal(s) of a set of target chemicals can be obtained without signals from the one or more non-target chemicals. Information about and differences between the molecular topologies of the first set of chemicals and the one or more unwanted chemicals can be used to design a sequence that suppresses the one or more unwanted chemicals while allowing acquisition of signal(s) from the first set of chemicals. These techniques can be employed to recover sharp peaks despite magnetic field inhomogeneities and susceptibility effects.