- Mountain View CA, US Erik Karrer - Los Altos CA, US Germaine Fuh - Pacifica CA, US Kristie Ibarra - San Jose CA, US Quan Zheng - Fremont CA, US Yao-ming Huang - San Mateo CA, US Lindsay Deis - San Bruno CA, US Christine Wolak - Burlingame CA, US Dominic Samuel Berns - Redwood City CA, US
Assignee:
23andMe, Inc. - Mountain View CA
International Classification:
C07K 16/28 C12N 5/16
Abstract:
The present invention provides binding proteins, such as antibodies and antigen-binding fragments, which specifically bind to human interleukin-1 receptor accessory protein (hu-IL1RAP) and fully block the IL-1, IL-33, and IL-36 intracellular signaling pathways. Compositions comprising such binding proteins and methods of making and using such binding proteins are also provided.