- Los Angeles CA, US Rajendra Makkar - Los Angeles CA, US
Assignee:
Cedars-Sinai Medical Center - Los Angeles CA
International Classification:
A61B 5/0215 A61B 5/0402 A61B 5/00
Abstract:
Described herein is a guide wire that includes one, two or multiple pressure transducers for use in TAVI. The guide wire may include an aortic pressure sensor spaced from a left ventricular pressure sensor with sufficient length to allow the aortic pressure sensor to be located in the aorta while the ventricular pressure sensor is simultaneously located in the left ventricle. The pressure readings between the left ventricle and aorta may be subtracted to determine an improved indication of the prognosis of a patient with intermediate post-TAVR aortic regurgitation after assessment with transesophageal echocardiography.
Modular Dis-Assembly Of Transcatheter Valve Replacement Devices And Uses Thereof
- Los Angeles CA, US Rajendra Makkar - Los Angeles CA, US
Assignee:
Cedars-Sinai Medical Center - Los Angeles CA
International Classification:
A61F 2/24
Abstract:
The present invention provides modular transcatheter valve replacement devices and methods of using the same to treat valvular heart diseases. Disclosed is a bottom module that contains a heart valve replacement, and a top module connected to the bottom module. The top module may be bio-absorbable, or may contain one or more severable joints that allow the top module to be removed after implantation. The removable or absorbable top portion serves to add additional length the structure to add in orientation during implantation, but is removed or absorbed to minimize the metal and other foreign material in a patient's body that could cause thrombosis or other reactions.
Anatomically-Orientated And Self-Positioning Transcatheter Mitral Valve
- Los Angeles CA, US Rajendra Makkar - Los Angeles CA, US
Assignee:
Cedars-Sinai Medical Center - Los Angeles CA
International Classification:
A61F 2/24
Abstract:
Described herein is a mitral valve and systems and methods for implanting the same. The mitral valve device is designed to easily orient to and conform to the mitral orifice natural morphology. This mitral valve system may be implanted using a system of 2 guide wires that facilitate orientation of the flat portion of the stent properly with the flat portion of the mitral valve that is adjacent to the aortic valve. Additionally, the disclosed valve may have multiple mounds distributed across the outer surface of the valve/stent complex so as to prevent or reduce paravalvular leak after implantation.