Randall Matthews

US Patent:

6545038, Apr 8, 2003

Filed:

Nov 6, 2000

Appl. No.:

09/707212

Inventors:

Biswanath De - Cincinnati OH
Stanislaw Pikul - Mason OH
Menyan Cheng - West Chester OH
Neil Gregory Almstead - Loveland OH
Randall Stryker Matthews - Cincinnati OH
Michael George Natchus - Glendale OH
Yetunde Olabisi Taiwo - West Chester OH

Assignee:

The Procter Gamble Company - Cincinnati OH

International Classification:

A61K 31675

US Classification:

514431, 514 79, 514 80, 514450, 540453, 540454, 540455, 540456, 540466, 540467, 540468

Abstract:

The invention provides compounds of formula as described in the claims, or an optical isomer, diastereomer or enantiomer thereof, or a pharmaceutically-acceptable salt, or biohydrolyzable amide, ester, or imide thereof are useful as inhibitors of metalloproteases. Also disclosed are pharmaceutical compositions and methods of treating diseases, disorders and conditions characterized by metalloprotease activity using these compounds or the pharmaceutical compositions containing them.

US Patent:

6716421, Apr 6, 2004

Filed:

Mar 5, 2001

Appl. No.:

09/799184

Inventors:

Garry Steven Garrett - Fairfield OH
Leo Timothy Laughlin - Mason OH
Randall Stryker Matthews - Cincinnati OH
Dale Edwin Barker - Hamilton OH
Daniel James Kinne - Cincinnati OH
Gary Eugene McKibben - Middletown OH
Christopher Miles Miller - Milford OH
Timothy Robert Probst - Cincinnati OH

Assignee:

University of Florida Research Foundation, Inc. - Gainesville FL

International Classification:

A01N 3100

US Classification:

424 84, 424DIG 11, 424646, 43131, 431321, 43124, 514 23, 514 24, 514 25, 514 27, 514 32, 514 33, 514 34, 514 35, 514 42, 514 43, 514 53, 514 54, 514183, 5142222, 5142288, 514243, 514244, 514245, 514247, 514277, 514315, 514317, 514327, 514329, 514331, 514332, 514335, 514352, 514354, 514355, 514356, 514361, 514364, 514381, 514394, 514395, 514399, 514400, 514407, 514417, 514460, 514471, 514532, 514533, 514544, 514546, 514616, 514617, 514619, 514620, 514622, 514633, 514637, 514646, 514648, 514657, 514734, 514729, 514730, 514731, 514736

Abstract:

This invention relates to devices, kits, and methods for eliminating termite colonies. The kits, devices, and methods employ a termiticidal bait matrix containing a) a termiticide selected such that the termiticide causes death to about 50 to about 100% of termites within about 24 to about 84 days after the termites begin to ingest the termiticide or the bait matrix comprising the termiticide, b) a cellulose containing material, and c) water. The termiticidal bait matrix can be used in a bait station installed in the ground. The kits are suitable to be used by consumers in their homes.

US Patent:

6969512, Nov 29, 2005

Filed:

Oct 10, 2002

Appl. No.:

10/268356

Inventors:

Garry Steven Garrett - Fairfield OH, US
Leo Timothy Laughlin - Mason OH, US
Randall Stryker Matthews - Cincinnati OH, US

Assignee:

The University of Florida Research Foundation, Inc. - Gainesville FL

International Classification:

A01N043/50
A01N043/52
A01N025/08
A01N025/34

US Classification:

424 84, 424410, 424413, 424414, 424416, 424488, 424DIG 11, 514394, 514395, 514396, 514399, 514400

Abstract:

This invention relates to devices, kits, and methods for eliminating termite colonies. The kits, devices, and methods employ a termiticidal bait matrix containing.

US Patent:

7030156, Apr 18, 2006

Filed:

Jun 17, 2002

Appl. No.:

10/172855

Inventors:

Garry Steven Garrett - Fairfield OH, US
Leo Timothy Laughlin - Mason OH, US
Randall Stryker Matthews - Cincinnati OH, US
Dale Edwin Barker - Hamilton OH, US
Daniel James Kinne - Cincinnati OH, US
Gary Eugene McKibben - Middletown OH, US
Christopher Miles Miller - Milford OH, US
Timothy Robert Probst - Cincinnati OH, US

Assignee:

University of Florida Research Foundation, Inc - Gainesville FL

International Classification:

A01N 31/00

US Classification:

514460, 549417

Abstract:

This invention relates to devices, kits, and methods for eliminating termite colonies. The kits, devices, and methods employ a termiticidal bait matrix containing.

US Patent:

7157078, Jan 2, 2007

Filed:

Feb 2, 2004

Appl. No.:

10/770195

Inventors:

Garry Steven Garren - Fairfield OH, US
Leo Timothy Laughlin - Mason OH, US
Randall Stryker Matthews - Cincinnati OH, US
Dale Edwin Barker - Hamilton OH, US
Daniel James Kinne - Cincinnati OH, US
Gary Eugene McKibben - Middletown OH, US
Christopher Miles Miller - Milford OH, US
Timothy Robert Probst - Cincinnati OH, US

Assignee:

The University of Florida Research Foundation, Inc. - Gainesville FL

International Classification:

A01N 31/00
A01N 33/02
A01N 37/00
A01N 37/02
A01N 37/06
A01N 43/40
A01N 43/54
A01N 43/66
A01N 25/00
A01N 25/02
A01N 25/08

US Classification:

424 84, 424646, 424DIG 11, 514 23, 514 24, 514 25, 514 27, 514 32, 514 33, 514 34, 514 35, 514 42, 514 43, 514 53, 514 54, 514183, 5142222, 5142288, 514243, 514244, 514245, 514247, 514277, 514315, 514317, 514327, 514329, 514331, 514336, 514361, 514364, 514381, 514394, 514395, 514396, 514399, 514400, 514407, 514417, 514460, 514471, 514532, 514533, 514544, 514546, 514616, 514617, 514619, 514620, 514622, 514633, 514637, 514646, 514648, 514657, 514729, 514730, 514731, 514734, 514736

Abstract:

This invention relates to devices, kits, and methods for eliminating termite colonies. The kits, devices, and methods employ a termiticidal bait matrix containing.

US Patent:

20030186958, Oct 2, 2003

Filed:

Feb 6, 2003

Appl. No.:

10/361115

Inventors:

Biswanath De - Cincinnati OH, US
Stanislaw Pikul - Mason OH, US
Menyan Cheng - West Chester OH, US
Neil Almstead - Loveland OH, US
Randall Matthews - Cincinnati OH, US
Michael Natchus - Glendale OH, US
Yetunde Taiwo - West Chester OH, US

Assignee:

The Procter & Gamble Company

International Classification:

A61K031/553
A61K031/554
A61K031/55
C07D267/02
C07D281/02
C07D243/08
C07D223/04

US Classification:

514/211010, 514/217110, 514/218000, 540/544000, 540/575000, 540/607000

Abstract:

The invention provides compounds of formula as described in the claims, or an optical isomer, diastereomer or enantiomer thereof, or a pharmaceutically-acceptable salt, or biohydrolyzable amide, ester, or imide thereof are useful as inhibitors of metalloproteases. Also disclosed are pharmaceutical compositions and methods of treating diseases, disorders and conditions characterized by metalloprotease activity using these compounds or the pharmaceutical compositions containing them.

US Patent:

56748914, Oct 7, 1997

Filed:

Jun 7, 1995

Appl. No.:

8/481726

Inventors:

Michael Wiard Scherz - West Chester OH
Randall Stryker Matthews - Cincinnati OH

Assignee:

The Procter & Gamble Company - Cincinnati OH

International Classification:

A61K 3138
C07D33354

US Classification:

514443

Abstract:

A compound having the structure: ##STR1## wherein (a) X is oxygen or sulfur; (b) each Y is independently hydrogen or unsubstituted straight, branched or cyclic alkanyl having from 1 to about 3 carbon atoms, or the two Y's are bonded to form an alkanyl ring having from 3 to about 7 carbon atoms; (c) Z is hydrogen or unsubstituted branched or cyclic alkyl, or unsubstituted or alkanyl-substituted phenyl, having from 3 to about 10 atoms other than hydrogen; (d) W is straight, branched or cyclic alkyl or aryl, unsubstituted or substituted, saturated or mono- or di-unsaturated with double bonds except that no terminal carbon atom of W is part of a double bond; W having from 1 to about 15 atoms other than hydrogen; pharmaceutical compositions comprising such compounds, and methods of treating inflammation or pain using such compounds.

US Patent:

45769621, Mar 18, 1986

Filed:

May 4, 1984

Appl. No.:

6/607351

Inventors:

Randall S. Matthews - Cincinnati OH

Assignee:

The Procter & Gamble Company - Cincinnati OH

International Classification:

C07C17700
A61K 31557

US Classification:

514530

Abstract:

The 13,14-didehydro-15-oxo analogues of natural prostaglandins possess high cytoprotective activity and low diarrheogenic activity, low anti-hemostatic activity and low smooth muscle contraction activity.