Sayed Elmarakby - Newtown PA, US Ping Cai - New City NY, US Appavu Chandrasekaran - Plainsboro NJ, US Mark Ruppen - Garnerville NY, US Rasmy Talaat - West Chester PA, US
Assignee:
Wyeth - Madison NJ
International Classification:
A61K 31/7052 A61K 31/423 C07D 263/52
US Classification:
514023000, 514375000, 536017400, 548216000
Abstract:
This invention provides estrogen receptor modulators of formula I, having the structure wherein Q, Q, R, R, R, R, R, and X as defined in the specification, or a pharmaceutically acceptable salt thereof.
Gary Stack - Ambler PA, US Christine Huselton - Royersford PA, US Jianyao Wang - Monmouth Junction NJ, US William Demaio - Collegeville PA, US Ronald Jordan - Richboro PA, US John Erve - Eagleville PA, US Rasmy Talaat - West Chester PA, US Matthew Hoffmann - Pottstown PA, US
Assignee:
Wyeth - Madison NJ
International Classification:
A61K 31/34 A61K 31/343 C07D 307/02
US Classification:
514469000, 549467000
Abstract:
Compounds of formula I are described herein which are agonists or partial agonists of the 2C subtype of brain serotonin receptors. or pharmaceutically acceptable salts thereof, wherein each of R, R, R, R, R, R, and n are as defined herein. Such compounds, and compositions thereof, are useful for treating a variety of central nervous system disorders such as schizophrenia.
Prodrug Substituted Benzoxazoles As Estrogenic Agents
Sayed Elmarakby - Newtown PA, US Ping Cai - New City NY, US Appavu Chandrasekaran - Plainsboro NJ, US Mark Ruppen - Garnerville NY, US Rasmy Talaat - West Chester PA, US
Assignee:
WYETH - Madison NJ
International Classification:
A61K 31/7052 A61K 31/423 C07D 263/52 C07H 15/22
US Classification:
514 23, 514375, 536 174, 548216
Abstract:
This invention provides estrogen receptor modulators of formula I, having the structurewherein
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