Raymond I Clark

US Patent:

20030224371, Dec 4, 2003

Filed:

Jun 4, 2002

Appl. No.:

10/160191

Inventors:

Bradley Thomas - Timonium MD, US
Alan Harper - Jamul CA, US
Charles Clemens - Encinitas CA, US
Raymond Clark - Oceanside CA, US
Robert Elms - San Diego CA, US
Lanny Gorton - San Diego CA, US
John Slate - San Diego CA, US
Richard Meyst - Valley Center CA, US

International Classification:

C12Q001/68
C12M001/34

US Classification:

435/006000, 435/287200

Abstract:

An integrated cartridge for automated sample manipulation and, particularly strand displacement amplification, is provided. The cartridge comprises a sealed, two-part device with internal fluid channels and chambers, as well as reagents. The cartridge performs the sequence of fluid transfers, reagent additions and heat transitions, such as those of the strand displacement amplification process, in a single, sealed device.

US Patent:

20060040311, Feb 23, 2006

Filed:

Oct 26, 2005

Appl. No.:

11/258123

Inventors:

Bradley Thomas - Timonium MD, US
Alan Harper - Jamul CA, US
Charles Clemens - Encinitas CA, US
Raymond Clark - Oceanside CA, US
Robert Elms - San Diego CA, US
Lanny Gorton - San Diego CA, US
John Slate - San Diego CA, US
Richard Meyst - Valley Center CA, US

Assignee:

Becton Dickinson and Company - Franklin Lakes NJ

International Classification:

C12Q 1/68
C12M 1/34

US Classification:

435006000, 435287200

Abstract:

An integrated cartridge for automated sample manipulation and, particularly strand displacement amplification, is provided. The cartridge comprises a sealed, two-part device with internal fluid channels and chambers, as well as reagents. The cartridge performs the sequence of fluid transfers, reagent additions and heat transitions, such as those of the strand displacement amplification process, in a single, sealed device.