Richard W Epstein

US Patent:

43320112, May 25, 1982

Filed:

Mar 17, 1980

Appl. No.:

6/130770

Inventors:

Richard A. Epstein - Tyngsboro MA
Henry A. Zannini - North Andover MA

Assignee:

Cambridge Telecommunications, Inc. - Burlington MA

International Classification:

G06F 946

US Classification:

364200

Abstract:

A data processing arrangement including a microprocessor and a plurality of input/output devices arranged in groups in accordance with a predetermined priority scheme. Each input/output device is capable of initiating a service request via an interrupt line to the microprocessor as a result of which a machine cycle is initiated by the microprocessor in which control signals are produced by the microprocessor and applied to logic circuitry coupled to the groups of input/output devices. The logic circuitry operates to propagate a low voltage level at the output of the input/output device initiating the service request down through the lower priority groups and to change inputs of the lower priority input/output devices from normal high voltage levels to low voltage levels. Data is then applied by the input/output device initiating the service request to the microprocessor, following which a microprocessor reset instruction resets the device. In accordance with the present invention, once a given input/output device has been pre-conditioned for resetting, the microprocessor and logic circuitry operate to prevent a change in this condition by preventing a low voltage level established at the output of another input/output device in a higher-priority group subsequently initiating a service request from being propagated to the input of the lower-priority input/output device.

US Patent:

55996817, Feb 4, 1997

Filed:

Oct 13, 1994

Appl. No.:

8/324421

Inventors:

Richard J. Epstein - Brookline MA
Charles D. Stiles - Newton MA

Assignee:

Dana-Farber Cancer Institute, Inc. - Boston MA

International Classification:

G01N 3353
G01N 33574

US Classification:

435 723

Abstract:

Activation-state-specific and protein-specific antiphosphoprotein antibodies and methods for their production are disclosed. Also disclosed are methods for evaluating the prognosis and therapeutic outcome for patients using the antiphosphoprotein antibodies and methods for characterizing the activation state of a reversibly phosphorylated protein, kits including the antibodies for use in characterizing the activation state of a protein, and methods for evaluating the agonist or antagonist activity of pharmaceutically useful compounds towards the conversion of a specific protein from its inactive to its active state.

US Patent:

62599453, Jul 10, 2001

Filed:

Apr 30, 1999

Appl. No.:

9/303501

Inventors:

Richard Epstein - Sharon MA
David G. Abichaker - Boston MA

Assignee:

UroMed Corporation - Norwood MA

International Classification:

A61B 505

US Classification:

600547

Abstract:

An improved method and device for locating a nerve based on a closed-loop automated system is described. The device applies an electro-stimulus to a target tissue area and measures and interprets a change in a response evoked by application of an electro-stimulus to determine the location and responsiveness of a nerve. The improvement of the invention comprises a method for determining if the signal of the response is stable prior to application of electro-stimulation to prevent misinterpretation of a response and to enhance the locating accuracy of the device.

US Patent:

20140351164, Nov 27, 2014

Filed:

May 22, 2013

Appl. No.:

13/899695

Inventors:

- Orion MI, US
Richard Alan Epstein - Aberdeen NJ, US

Assignee:

ANS Tech, LLC - Orion MI

International Classification:

G06Q 10/08
G01C 21/34

US Classification:

705338

Abstract:

A method for sequencing geo coded addresses on a delivery route with the use of a device is disclosed, The methodology includes the steps of a driver selecting a street segment on a device and selecting a sequence mode for the delivery. The methodology also includes driving down a selected street segment and confirming an odd or even number of the addresses on either side of the street. The methodology also comprises the marking of each address as delivered as it is passed by the driver.