Richard K Willis

Address:

10914 Long Br Dr, Austin, TX 78736

VIN:

1GNKRFED0BJ310280

Make:

CHEVROLET

Model:

TRAVERSE

Year:

2011

Address:

5705 Eagle Claw Ave, Las Vegas, NV 89130

VIN:

1ZVFT80N775292610

Make:

FORD

Model:

MUSTANG

Year:

2007

US Patent:

53167651, May 31, 1994

Filed:

Sep 19, 1991

Appl. No.:

7/762312

Inventors:

Karl A. Folkers - Austin TX
Per H. Langsjoen - Temple TX
Richard A. Willis - Austin TX

Assignee:

Karl Folkers Foundation for Biomedical and Clinical Research - Austin TX

International Classification:

A61K 4500
A61K 31405
A61K 3135
A61K 3112

US Classification:

424 941

Abstract:

Disclosed are methods for inhibiting the side effects attendant treatment with HMG-CoA reductase inhibitors. Treatment of a patient with and HMG-CoA reductase inhibitor in combination with coenzyme Q. sub. 10 provides a reduction in patient cholesterol levels and guards against typical HMG-CoA reductase-inhibitor side effects, most notably liver dysfunction and cardiac dysfunction. The combination of lovastatin, an HMG-CoA reductase inhibitor, and coenzyme Q. sub. 10 in ratios of between 1:2 to 1:29 provide significant enhancement of a patient's caridac condition. By way of example, other HMG-CoA reductase inhibitors which may be included in the claimed combinations include pravastatin, compactin, fluvastatin, dalvastatin, simvastatin, BMY 22089, GR-95030, HR-780, CI-981, SQ 33,600, and BMY 22566 and XU-62-320.