Robert A Booth

US Patent:

20120282267, Nov 8, 2012

Filed:

May 2, 2012

Appl. No.:

13/462587

Inventors:

Robert Booth - Los Altos Hills CA, US

Assignee:

ViroBay, Inc. - Menlo Park CA

International Classification:

A61K 31/165
A61P 35/04
A61P 25/00
A61K 39/395

US Classification:

4241461, 514616

Abstract:

The present invention is directed to methods of using compounds that are inhibitors of cysteine proteases, in particular, of both cathepsins S and K and optionally further cathepsins B and/or L in treating bone cancer. The present invention is directed to pharmaceutical compositions comprising these compounds for treating bone cancer and bone cancer pain, especially the pain associated with metastasis. A single compound can be used to ameliorate the pain, the injury to bone, while also reducing tumor growth, the risk of metastasis and/or invasiveness of the cancer.

US Patent:

20120329837, Dec 27, 2012

Filed:

Jun 18, 2012

Appl. No.:

13/525845

Inventors:

Robert Booth - Los Altos Hills CA, US

Assignee:

ViroBay, Inc. - Menlo Park CA

International Classification:

A61K 31/277
A61P 25/00
A61P 25/16
A61K 31/4406
A61P 25/28

US Classification:

514357, 514521

Abstract:

The present invention concerns methods of using Cathepsin S inhibitors and compounds of Formula I that are inhibitors of cathepsin S in treating CNS disorders, diseases, and injuries, particularly neurodegenerative conditions. The present invention is directed to pharmaceutical compositions comprising these compounds for treating CNS disorders.

US Patent:

39981614, Dec 21, 1976

Filed:

Jun 30, 1975

Appl. No.:

5/591836

Inventors:

Robert C. Booth - Hayward CA

International Classification:

F42B 526

US Classification:

102 43R

Abstract:

A device for adapting a cartridge having a bottleneck casing to be fired in a standard revolver includes a cylindrical sleeve received about the bottleneck portion to provide a smooth cylindrical exterior for the cartridge. The sleeve bore includes a tapered portion to impinge on the oblique portion of the bottleneck. The sleeve is retained by a press fit on the cartridge.

US Patent:

20220267325, Aug 25, 2022

Filed:

Apr 20, 2022

Appl. No.:

17/725220

Inventors:

- Menlo Park CA, US
Robert BOOTH - Los Altos Hills CA, US
Michael J. GREEN - Half Moon Bay CA, US

International Classification:

C07D 471/04
C07D 519/00

Abstract:

Disclosed herein are compounds that can inhibit 15-hydroxyprostaglandin dehydrogenase. Such compounds may be administered to subjects that may benefit from modulation of prostaglandin levels.