Robert I Booth

US Patent:

20120282267, Nov 8, 2012

Filed:

May 2, 2012

Appl. No.:

13/462587

Inventors:

Robert Booth - Los Altos Hills CA, US

Assignee:

ViroBay, Inc. - Menlo Park CA

International Classification:

A61K 31/165
A61P 35/04
A61P 25/00
A61K 39/395

US Classification:

4241461, 514616

Abstract:

The present invention is directed to methods of using compounds that are inhibitors of cysteine proteases, in particular, of both cathepsins S and K and optionally further cathepsins B and/or L in treating bone cancer. The present invention is directed to pharmaceutical compositions comprising these compounds for treating bone cancer and bone cancer pain, especially the pain associated with metastasis. A single compound can be used to ameliorate the pain, the injury to bone, while also reducing tumor growth, the risk of metastasis and/or invasiveness of the cancer.

US Patent:

20120329837, Dec 27, 2012

Filed:

Jun 18, 2012

Appl. No.:

13/525845

Inventors:

Robert Booth - Los Altos Hills CA, US

Assignee:

ViroBay, Inc. - Menlo Park CA

International Classification:

A61K 31/277
A61P 25/00
A61P 25/16
A61K 31/4406
A61P 25/28

US Classification:

514357, 514521

Abstract:

The present invention concerns methods of using Cathepsin S inhibitors and compounds of Formula I that are inhibitors of cathepsin S in treating CNS disorders, diseases, and injuries, particularly neurodegenerative conditions. The present invention is directed to pharmaceutical compositions comprising these compounds for treating CNS disorders.

US Patent:

42071879, Jun 10, 1980

Filed:

May 5, 1976

Appl. No.:

5/683547

Inventors:

Robert G. Booth - Oakland CA

International Classification:

B01D 2710

US Classification:

210130

Abstract:

A system for externally cooling and/or filtering oil involving an internally and externally finned housing enclosing a replaceable filter in flow alignment with the external cooling flow circuit of an automatic transmission or the like.

US Patent:

39981614, Dec 21, 1976

Filed:

Jun 30, 1975

Appl. No.:

5/591836

Inventors:

Robert C. Booth - Hayward CA

International Classification:

F42B 526

US Classification:

102 43R

Abstract:

A device for adapting a cartridge having a bottleneck casing to be fired in a standard revolver includes a cylindrical sleeve received about the bottleneck portion to provide a smooth cylindrical exterior for the cartridge. The sleeve bore includes a tapered portion to impinge on the oblique portion of the bottleneck. The sleeve is retained by a press fit on the cartridge.

US Patent:

42197104, Aug 26, 1980

Filed:

Apr 15, 1976

Appl. No.:

5/677281

Inventors:

Robert G. Booth - Oakland CA

Assignee:

Stop Alert Corporation - Oakland CA

International Classification:

H01H 3534

US Classification:

200 81R

Abstract:

A pressure change responsive sensor and related vacuum operable switch assembly capable of operation from the manifold of an internal combustion engine to activate a signal in anticipation of the application of the brakes of an automobile. The vacuum operable switch assembly is an improvement on the applicant's U. S. Pat. No. 3,639,898 for Differential Pressure Control System And Switch Means Therefor, and is capable of adjustment to function with internal combustion engines having different manifold vacuum characteristics.

US Patent:

40472493, Sep 13, 1977

Filed:

Dec 29, 1975

Appl. No.:

5/644848

Inventors:

Robert G. Booth - Oakland CA

International Classification:

A42B 300
A61F 902

US Classification:

2 10

Abstract:

A protective helmet for use by race drivers, police riot squads. etc. incorporates a face shield assembly involving means for overcoming problems of breakage, glare and fogging by associating with a face shield of substantially unbreakable material, coatings or layers of polarized and/or light effecting material treated for fog prevention.

US Patent:

20220267325, Aug 25, 2022

Filed:

Apr 20, 2022

Appl. No.:

17/725220

Inventors:

- Menlo Park CA, US
Robert BOOTH - Los Altos Hills CA, US
Michael J. GREEN - Half Moon Bay CA, US

International Classification:

C07D 471/04
C07D 519/00

Abstract:

Disclosed herein are compounds that can inhibit 15-hydroxyprostaglandin dehydrogenase. Such compounds may be administered to subjects that may benefit from modulation of prostaglandin levels.