Robert P Canfield

US Patent:

6339143, Jan 15, 2002

Filed:

Jun 7, 1995

Appl. No.:

08/487949

Inventors:

Alexander Krichevsky - Fox Chapel PA
Steven Birken - Dumont NJ
John OConnor - New Rochelle NY
Robert E. Canfield - Cold Spring NY

Assignee:

The Trustees of Columbia University in the City of New York - New York NY

International Classification:

K07K 6126

US Classification:

53038824, 5303881, 435325, 435326, 435336

Abstract:

This invention provides methods for detecting the presence of human malignant cells in a sample of tumor cells; determining whether a tumor present in a human subject is malignant; obtaining an enriched population of live human malignant cells; determining the amount of intact luteinizing hormone in a sample; determining the ovulatory stage of a subject; determining the amount of intact follicle stimulating hormone in a sample; determining the ovulatory stage of a subject; determining the amount of intact human chorionic gonadotropin in a sample; determining whether a subject is pregnant; determining the ovulatory stage of a subject; determining the amount of free subunit of human luteinizing hormone in a sample; determining whether a subject has a malignant tumor; determining the amount of nicked human chorionic gonadotropin in a sample; and determining the likelihood of a fetuss being afflicted with Downs syndrome.