Robert Clark Cheek from 1208 West Pt, Sanford, NC 27332, age 74, Phone: (828)2426873

License Records

Robert Tines Cheek Md

License #:

14692 - Expired

Category:

Medicine

Issued Date:

Jul 25, 1978

Effective Date:

Dec 1, 1983

Type:

Physician

Us Patents

He4 Monoclonal Antibodies And Methods For Their Use
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US Patent:

7846692, Dec 7, 2010
Filed:

Mar 7, 2008
Appl. No.:

12/044302
Inventors:

Robert L. Cheek - Mebane NC, US
Timothy J. Fischer - Raleigh NC, US
John W. Groelke - Raleigh NC, US
Assignee:

Tripath Imaging, Inc. - Burlington NC
International Classification:

C12P 21/04
US Classification:

435 7021, 4241841, 5303871
Abstract:

Compositions and methods for diagnosing ovarian cancer in a patient and for identifying patients with an increased likelihood of having ovarian cancer are provided. The compositions include novel monoclonal antibodies, and variants and fragments thereof, that specifically bind to HE4. Monoclonal antibodies having the binding characteristics of an HE4 antibody of the invention are further provided. Hybridoma cell lines that produce an HE4 monoclonal antibody of the invention are also disclosed herein. The compositions find use in diagnostic methods as well as in screening methods for identifying patients having an increased likelihood of having ovarian cancer. Kits comprising one or more of the disclosed HE4 monoclonal antibodies and for practicing the methods of the invention are further provided. Polypeptides comprising the amino acid sequence for an HE4 epitope and methods of using these polypeptides in the production of antibodies are also encompassed by the present invention.

Glycodelin Monoclonal Antibodies And Methods For Their Use In The Detection Of Ovarian Cancer
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US Patent:

8252904, Aug 28, 2012
Filed:

Mar 5, 2010
Appl. No.:

12/718693
Inventors:

Robert L. Cheek - Mebane NC, US
Eric P. Dixon - Cary NC, US
Timothy J. Fischer - Raleigh NC, US
John W. Groelke - Raleigh NC, US
Steven L. Knapp - Apex NC, US
Stephen G. Simkins - Fuquay-Varina NC, US
Clark M. Whitehead - Apex NC, US
Assignee:

Tripath Imaging, Inc. - Burlington NC
International Classification:

C07K 16/00
C07K 14/00
C07K 5/00
G01N 33/53
US Classification:

5303871, 5303879, 5303881, 530330, 530324, 530395, 435 71
Abstract:

Compositions and methods for diagnosing ovarian cancer in a patient and for identifying patients with an increased likelihood of having ovarian cancer are provided. The compositions include novel monoclonal antibodies, and variants and fragments thereof, that specifically bind to glycodelin. Monoclonal antibodies having the binding characteristics of a glycodelin antibody of the invention and monoclonal antibodies that bind to a glycodelin epitope of a disclosed antibody are further provided. Hybridoma cell lines that produce a glycodelin monoclonal antibody of the invention are also disclosed herein. The compositions find use in diagnostic methods as well as in screening methods for identifying patients having an increased likelihood of having ovarian cancer. Kits comprising one or more of the disclosed glycodelin monoclonal antibodies and for practicing the methods of the invention are further provided. Polypeptides comprising the amino acid sequence for a glycodelin epitope of a disclosed monoclonal glycodelin antibody and methods of using these polypeptides in the production of glycodelin antibodies are also encompassed by the present invention.

Glycodelin Monoclonal Antibodies And Methods For Their Use In The Detection Of Ovarian Cancer
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US Patent:

8476033, Jul 2, 2013
Filed:

Jul 27, 2012
Appl. No.:

13/560080
Inventors:

Robert L. Cheek - Mebane NC, US
Eric P. Dixon - Cary NC, US
Timothy J. Fischer - Raleigh NC, US
John W. Groelke - Raleigh NC, US
Steven L. Knapp - Apex NC, US
Stephen G. Simkins - Fuquay-Varina NC, US
Clark M. Whitehead - Cary NC, US
Assignee:

TriPath Imaging, Inc. - Burlington NC
International Classification:

G01N 33/00
C07K 16/00
US Classification:

435 792, 435 794, 435 71, 435 72, 5303871, 5303881, 530350, 436 64
Abstract:

Compositions and methods for diagnosing ovarian cancer in a patient and for identifying patients with an increased likelihood of having ovarian cancer are provided. The compositions include novel monoclonal antibodies, and variants and fragments thereof, that specifically bind to glycodelin. Monoclonal antibodies having the binding characteristics of a glycodelin antibody of the invention and monoclonal antibodies that bind to a glycodelin epitope of a disclosed antibody are further provided. Hybridoma cell lines that produce a glycodelin monoclonal antibody of the invention are also disclosed herein. Kits comprising one or more of the disclosed glycodelin monoclonal antibodies and for practicing the methods of the invention are further provided. Polypeptides comprising the amino acid sequence for a glycodelin epitope of a disclosed monoclonal glycodelin antibody and methods of using these polypeptides in the production of glycodelin antibodies are also encompassed by the present invention.

He4 Monoclonal Antibodies And Methods For Their Use
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US Patent:

20110038883, Feb 17, 2011
Filed:

Oct 29, 2010
Appl. No.:

12/915200
Inventors:

Robert L. Cheek - Mebane NC, US
Timothy J. Fischer - Raleigh NC, US
John W. Groelke - Raleigh NC, US
Assignee:

TriPath Imaging, Inc - Burlington NC
International Classification:

A61K 39/00
C07K 16/18
C12N 5/16
G01N 33/53
C07K 7/06
C07K 7/08
C07K 14/00
C07H 21/04
C12P 21/06
US Classification:

4241841, 5303882, 435332, 435 71, 530327, 530325, 530326, 536 231, 435 696
Abstract:

Compositions and methods for diagnosing ovarian cancer in a patient and for identifying patients with an increased likelihood of having ovarian cancer are provided. The compositions include novel monoclonal antibodies, and variants and fragments thereof, that specifically bind to HE4. Monoclonal antibodies having the binding characteristics of an HE4 antibody of the invention are further provided. Hybridoma cell lines that produce an HE4 monoclonal antibody of the invention are also disclosed herein. The compositions find use in diagnostic methods as well as in screening methods for identifying patients having an increased likelihood of having ovarian cancer. Kits comprising one or more of the disclosed HE4 monoclonal antibodies and for practicing the methods of the invention are further provided. Polypeptides comprising the amino acid sequence for an HE4 epitope and methods of using these polypeptides in the production of antibodies are also encompassed by the present invention.

Methods And Compositions For Detecting Mycoplasma Exposure
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US Patent:

20170219604, Aug 3, 2017
Filed:

Jan 27, 2017
Appl. No.:

15/418477
Inventors:

- Morrisville NC, US
Melissa E. Langer - Morrisville NC, US
Jasper N. Pollard - Durham NC, US
Robert L. Cheek - Mebane NC, US
Kevin G. Dolan - Holly Springs NC, US
W. William Stewart - Cary NC, US
Stefano Bresolin - Garner NC, US
John Richard Sink - Raleigh NC, US
Tobias M. Heineck - Durham NC, US
Laura A. Black - Holly Springs NC, US
Nathan F. Pope - Raleigh NC, US
Lauren K. Parker - Edenton NC, US
Erik J. Jensen - Hillsborough NC, US
Jorge Carlos Correa - Raleigh NC, US
Reha O. Azizoglu - Morrisville NC, US
International Classification:

G01N 33/68
Abstract:

The present invention provides methods and compositions for detecting exposure in a subject.

Sample Cartridge And Sample Stage
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US Patent:

20140315283, Oct 23, 2014
Filed:

May 9, 2013
Appl. No.:

14/239894
Inventors:

David A. Calderwood - Chapel Hill NC, US
Rodolfo Rodriguez - Cary NC, US
Demetris Young - Durham NC, US
Jasper N. Pollard - Durham NC, US
Robert L. Cheek - Mebane NC, US
Duane Olsen - Hillsborough NC, US
John Groelke - Raleigh NC, US
Reha Azizoglu - Morrisville NC, US
Mitch Hockett - Raleigh NC, US
David Newcomb - Morrisville NC, US
Tobias M. Heineck - Durham NC, US
Joy Parr Drach - Pontiac IL, US
International Classification:

G01N 33/569
US Classification:

4352872
Abstract:

A sample cartridge () for microscopic imaging of a biological sample comprises a body having an end portion () and a pair of generally parallel opposing side edge portions (), a locking edge portion () formed on the body; a carrier removably connected to or permanently connected to the body; and at least one anti-analyte antibody coupled to either the carrier or to the chamber () side wall portion (e.g., at the surface to be imaged, or supporting the sample to be imaged). An XYZ stage () for receiving such a cartridge () is also described.

Autofocus Method For Imaging A Biological Sample And Cartridge For Use Therein
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US Patent:

20140186859, Jul 3, 2014
Filed:

May 9, 2013
Appl. No.:

14/240202
Inventors:

- Durham NC, US
Rodolfo R. Rodriguez - Cary NC, US
Tobias M. Heineck - Durham NC, US
Stefano Bresolin - Gamer NC, US
Chris Paul - Hillsborough NC, US
Demetris Young - Durham NC, US
Jasper N. Pollard - Durham NC, US
David Newcomb - Morrisville NC, US
Robert L. Cheek - Mebane NC, US
Reha Azizoglu - Morrisville NC, US
Mitch Hockett - Releigh NC, US
Duane Olsen - Hillsborough NC, US
John Groelke - Raleigh NC, US
International Classification:

G01N 33/569
G02B 21/36
G01N 21/64
US Classification:

435 732, 422554, 348 79
Abstract:

A method of automatically focusing a microscope on a specimen is carried out by capturing an image from each of a plurality of focal planes in or on said specimen, calculating a focus score for each of said images, selecting the focal plane corresponding to the image having the best focus score, and then repositioning said specimen relative to said microscope so that said microscope is focused on said selected focal plane, the method includes a plurality of exogenous targets in or on said specimen, which aids in focusing in the event particular objects of interest, such as cells/pathogens that may or may not be in the sample, are not present, or are present in low numbers. Automated microscopes and microscope cartridges useful in such methods are also described, along with methods of detecting pathogens in biological samples.

Medicine Doctors

Robert T. Cheek

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Specialties:

Internal Medicine

Work:

Internal Medicine South Clinic
4110 Outpatient Cir STE 2508, Little Rock, AR 72205
(501)6865545 (phone), (501)6868765 (fax)

Education:

Medical School
University of Arkansas College of Medicine at Little Rock
Graduated: 1976

Procedures:

Cardiac Stress Test
Destruction of Benign/Premalignant Skin Lesions
Vaccine Administration
Nutrition Therapy

Conditions:

Abdominal Hernia
Abnormal Vaginal Bleeding
Acne
Anemia
Atrial Fibrillation and Atrial Flutter

Languages:

English
Spanish

Description:

Dr. Cheek graduated from the University of Arkansas College of Medicine at Little Rock in 1976. He works in Little Rock, AR and specializes in Internal Medicine.

Robert F. Cheek

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Specialties:

Anatomic Pathology & Clinical Pathology

Work:

Boyce & Bynum Pathology Laboratories
200 Portland St, Columbia, MO 65201
(573)8864600 (phone), (573)8864695 (fax)

Education:

Medical School
University of Missouri, Columbia School of Medicine
Graduated: 1990

Languages:

English

Description:

Dr. Cheek graduated from the University of Missouri, Columbia School of Medicine in 1990. He works in Columbia, MO and specializes in Anatomic Pathology & Clinical Pathology.