Robert Jay DeFranco - Wilmington DE Richard M. Scribner - Wilmington DE
Assignee:
E. I. Du Pont de Nemours and Company - Wilmington DE
International Classification:
C07D20728 C07D20730
US Classification:
2603262
Abstract:
Certain 1,5-disubstituted 2-pyrrolidinones, and their ring unsaturated analogs, resemble natural prostaglandins. The compounds are easier to prepare than the prostaglandins since they have at least one fewer center of asymmetry and accordingly fewer isomers are produced. Exemplary is 7-[2-oxo-5-(3-hydroxy-1-oct-1-enyl)-1-pyrrolidinyl]heptanoic acid of the formula: ##SPC1##.