Robert M Defranco

US Patent:

39753999, Aug 17, 1976

Filed:

Aug 6, 1974

Appl. No.:

5/495199

Inventors:

Robert Jay DeFranco - Wilmington DE
Richard M. Scribner - Wilmington DE

Assignee:

E. I. Du Pont de Nemours and Company - Wilmington DE

International Classification:

C07D20728
C07D20730

US Classification:

2603262

Abstract:

Certain 1,5-disubstituted 2-pyrrolidinones, and their ring unsaturated analogs, resemble natural prostaglandins. The compounds are easier to prepare than the prostaglandins since they have at least one fewer center of asymmetry and accordingly fewer isomers are produced. Exemplary is 7-[2-oxo-5-(3-hydroxy-1-oct-1-enyl)-1-pyrrolidinyl]heptanoic acid of the formula: ##SPC1##.