Robert F Devlin

Address:

120 Wallace Rd, Tumbling Shoals, AR 72581

Phone:

(501)3622667

VIN:

2FMDK3JC0BBA57222

Make:

FORD

Model:

EDGE

Year:

2011

US Patent:

6670117, Dec 30, 2003

Filed:

May 7, 2001

Appl. No.:

09/850022

Inventors:

Preston H. Dorsett - Memphis TN
Frances I. Byrd - Memphis TN
Robert F. Devlin - Cordova TN

Assignee:

Viral Antigens, Inc. - Memphis TN

International Classification:

C12Q 170

US Classification:

435 5, 435 71, 435 79, 5303883, 530395, 4242191

Abstract:

This invention particularly discloses an improved immunoassay method for the specific detection of anti-rubella IgM antibodies. This method employs rubella antigens comprising rubella E1 and E2 envelope glycoproteins substantially free of capsid protein. Use of this antigen composition reduces or eliminates nonspecific protein-protein interactions leading to false positive results. A sample diluent comprising urea can also be used in the process to further reduce the occurrence of nonspecific protein-protein interactions. A diagnostic kit to aid in the detection of anti-rubella IgM antibodies is also disclosed.

US Patent:

6872396, Mar 29, 2005

Filed:

Oct 29, 2003

Appl. No.:

10/696635

Inventors:

Preston H. Dorsett - Memphis TN, US
Frances I. Byrd - Memphis TN, US
Robert F. Devlin - Cordova TN, US

Assignee:

Viral Antigens, Inc. - Memphis TN

International Classification:

A61K039/20
A61K039/12
C07K014/19
G01N033/53

US Classification:

4242191, 4241841, 4242041, 530350, 530395, 435 4, 435 5, 435 79, 435 792

Abstract:

This invention particularly discloses an improved immunoassay method for the specific detection of anti-rubella IgM antibodies. This method employs rubella antigens comprising rubella E1 and E2 envelope glycoproteins substantially free of capsid protein. Use of this antigen composition reduces or eliminates nonspecific protein-protein interactions leading to false positive results. A sample diluent comprising urea can also be used in the process to further reduce the occurrence of nonspecific protein-protein interactions. A diagnostic kit to aid in the detection of anti-rubella IgM antibodies is also disclosed.

US Patent:

20080188007, Aug 7, 2008

Filed:

Feb 6, 2007

Appl. No.:

11/702812

Inventors:

K. John Morrow - Newport KY, US
Xiaokang Deng - Cincinnati OH, US
Robert F. Devlin - Tumbling Shoals AR, US
Preston H. Dorsett - Memphis TN, US

International Classification:

G01N 33/566
C07K 16/44

US Classification:

436501, 5303913

Abstract:

A fluorescent single chain antibody construct is provided comprising a single chain antibody reactive with a target analyte and conjugated with a fluorophore. Also provided is a method for rapid and accurate detection of analytes using the fluorescent single chain antibody construct thereof. Further provided is a diagnostic kit for detecting pathogens using a fluorescent single chain antibody construct comprising a single chain antibody reactive with pathogen-related antigens and conjugated with a fluorophore.

US Patent:

58467033, Dec 8, 1998

Filed:

Mar 23, 1993

Appl. No.:

8/035633

Inventors:

Robert F. Devlin - San Diego CA
Walter B. Dandliker - La Jolla CA
Peter O. G. Arrhenius - San Diego CA

Assignee:

Diatron Corporation - San Diego CA

International Classification:

G01N 33533

US Classification:

435 5

Abstract:

Fluorescence immunoassays methods are provided which use fluorescent dyes which are free of aggregation and serum binding. Such immunoassay methods are thus, particularly useful for the assay of biological fluids, such as serum, plasma, whole blood and urine.

US Patent:

56060459, Feb 25, 1997

Filed:

Apr 21, 1993

Appl. No.:

8/051446

Inventors:

Walter B. Dandliker - La Jolla CA
Robert F. Devlin - San Diego CA

Assignee:

Diatron Corporation - San Diego CA

International Classification:

C07H 2102
C07H 2104

US Classification:

536 2532

Abstract:

The present invention is directed to compositions comprising an oligonucleotide linked to a detectably labeled marker component comprising a fluorophore moiety which comprises a substantially planar, multidentate macrocyclic ligand coordinated to a central atom capable of coordinating with two axial ligands and two polyoxyhydrocarbyl moieties which are attached as axial ligands to the central atom. The present invention is also directed to nucleic acid hybridization and amplification methods employing such compositions.

US Patent:

58802878, Mar 9, 1999

Filed:

Jun 7, 1995

Appl. No.:

8/476544

Inventors:

Walter B. Dandliker - La Jolla CA
Robert Francis Devlin - San Diego CA
Peter Olaf Gustaf Arrhenius - San Diego CA
Mao-Lin Hsu - Fountain Valley CA

Assignee:

Hyperion, Inc. - Miami FL

International Classification:

C09B 2300
C07D51302

US Classification:

548156

Abstract:

Fluorescent dyes which are free of aggregation and serum binding are provided. These dyes are suitable for applications such as fluorescence immunoassays, in vivo imaging and in vivo tumor therapy. Fluorescence immunoassays methods are provided which use fluorescent dyes which are free of aggregation and serum binding. Such immunoassay methods are thus, particularly useful for the assay of biological fluids, such as serum, plasma, whole blood and urine. The present invention is directed to compositions comprising an oligonucleotide linked to a detectably labeled marker component comprising a fluorophore moiety which comprises a substantially planar, multidentate macrocyclic ligand coordinated to a central atom capable of coordinating with two axial ligands and two polyoxyhydrocarbyl moieties which are attached as axial ligands to the central atom. The present invention is also directed to nucleic acid hybridization and amplification methods employing such compositions.

US Patent:

57078130, Jan 13, 1998

Filed:

Sep 6, 1996

Appl. No.:

8/709285

Inventors:

Walter B. Dandliker - La Jolla CA
Robert F. Devlin - San Diego CA

Assignee:

Diatron Corporation - San Diego CA

International Classification:

C12Q 168
C12P 1934

US Classification:

435 6

Abstract:

The present invention is directed to compositions comprising an oligonucleotide linked to a detectably labeled marker component comprising a fluorophore moiety which comprises a substantially planar, multidentate macrocyclic ligand coordinated to a central atom capable of coordinating with two axial ligands and two polyoxyhydrocarbyl moieties which are attached as axial ligands to the central atom. The present invention is also directed to nucleic acid hybridization and amplification methods employing such compositions.

US Patent:

60605987, May 9, 2000

Filed:

Jun 13, 1997

Appl. No.:

8/874820

Inventors:

Robert Francis Devlin - San Diego CA
Walter Beach Dandliker - La Jolla CA
Peter Olaf Gustaf Arrhenius - San Diego CA

Assignee:

Hyperion, Inc. - Miami FL

International Classification:

C07D48722

US Classification:

540122

Abstract:

Fluorescence immunoassays methods are provided which use fluorescent dyes which are free of aggregation and serum binding. Such immunoassay methods are thus, particularly useful for the assay of biological fluids, such as serum, plasma, whole blood and urine.