Robert J Fields

US Patent:

20030027203, Feb 6, 2003

Filed:

Sep 12, 2002

Appl. No.:

10/243521

Inventors:

Robert Fields - Palo Alto CA, US

International Classification:

C12Q001/68
C07H021/02
C07H021/04
C12N001/08
C12M001/34

US Classification:

435/006000, 435/270000, 536/025400, 435/287200

Abstract:

A process and apparatus for isolating and purifying nucleic acids and other target molecules directly from blood, plasma, urine, cell cultures and the like by totally automated means, without centrifugation, aspiration or vacuum. After mixing a sample containing target molecules with a test reagent in an environmentally isolated compartment, target molecules are adsorbed onto a binding material and eluted in a small volume using an elution reagent. A preferred embodiment purifies nucleic acids and automatically detects target sequences from a sample of fresh blood.

US Patent:

45292272, Jul 16, 1985

Filed:

Jun 6, 1983

Appl. No.:

6/501647

Inventors:

Robert J. Fields - Burlingame CA

International Classification:

B41L 100
B41L 136
B42D 1500

US Classification:

282 5

Abstract:

A device for introducing forms into a printer of a computer to facilitate alignment of the forms with respect to the printer and to obviate wasted forms. Said device comprises a flexible sheet having a row of holes disposed along at least one edge of the sheet, means for removably attaching the forms to the flexible sheet and at least one reference line printed on the surface of the sheet for aligning the forms with respect to the printer. Said means can additionally comprise at least one self-adhesive area disposed on the surface of the flexible sheet for removably attaching the pre-printed form thereto.

US Patent:

58405739, Nov 24, 1998

Filed:

Oct 3, 1996

Appl. No.:

8/687589

Inventors:

Robert E. Fields - Palo Alto CA

International Classification:

C12M 100
C12M 302
B01L 300
G05D 2300

US Classification:

4352872

Abstract:

A molecular analyzer and method of use for sensitive, rapid and accurate detection of specific, or target, molecules or specific parts of molecules in a liquid sample to be detected without the use of radioisotopes. Apparatus for sealingly holding any number of sample tubes (23) containing a test sample and having pre-incorporated, internally contained detection reagents for removing unbound molecules from the sample tubes, as well as means for rapidly changing the temperature of the test sample and means for quantitating the target molecules without allowing molecules in the sample tube to contact the environment is provided. Alternatively, the apparatus may be adapted to receive detection reagents that are not preincorporated without exposing them or the test sample to the atmosphere.

US Patent:

45253994, Jun 25, 1985

Filed:

Jun 6, 1983

Appl. No.:

6/501509

Inventors:

Robert J. Fields - Burlingame CA

International Classification:

B32B 324

US Classification:

428 43

Abstract:

A manufactured article for reinforcing continuous forms having sprocket holes comprising a means for reinforcing the sprocket holes and alternatively additionally comprises means for reinforcing perforations found in said continuous forms. Said article comprises a continuous pliable strip having self-adhesive disposed on one side thereof and having a row of holes disposed therein with uniform spacing therebetween. The strip additionally has perforations which are transverse to the longitudinal axis of the strip and are disposed between alternative holes of the strip. The article may additionally comprise reinforcing tabs projecting from one edge of the strip to provide supplemental reinforcing means to the article.