Robert Kelly Frazer

US Patent:

40701131, Jan 24, 1978

Filed:

May 5, 1976

Appl. No.:

5/683267

Inventors:

Robert E. Frazer - La Canada CA
Marylou Ingram - Los Alamos NM

Assignee:

California Institute of Technology - Pasadena CA

International Classification:

G01N 2100
G01N 3316
H01J 3912

US Classification:

356104

Abstract:

A system for classifying the various major types of blood cells is provided wherein blood cells are passed before a laser beam. The redirected light energy passing through the cell is applied to a detector array which provides a voltage spectrum representative of the spatial relationships of the object. This voltage spectrum is compared rapidly with different spectra representative of different blood cell classes. Whenever a best fit is detected by the comparing means, a count is scored in one of the cell classes. The same means is applicable to the analysis of other cell types such as cancer and exfoliated cells.

US Patent:

41766628, Dec 4, 1979

Filed:

Jun 17, 1977

Appl. No.:

5/807597

Inventors:

Robert E. Frazer - La Canada CA

Assignee:

The United States of America as represented by the Administrator of the
National Aeronautics and Space Administration - Washington DC

International Classification:

A61B 106
A61M 2500

US Classification:

128 6

Abstract:

An endoscope is disclosed having a propulsion mechanism and at least one transmitter at the distal end transmitting bursts of energy waves (radio frequency or ultrasonic) for tracking the position of the distal end through the use of two or more transducers on the anterior or lateral surfaces of a patient. The propulsion mechanism may consist of two radially expandable bladders separated by an axially expandable bellows with only the forward bladder attached to the distal end so that by expanding and contracting them in proper sequence, propulsion of the endoscope is achieved. Alternate mechanisms comprise compliant paddles on the distal end directly on an articulated section, or compliant paddles on a rotatable sleeve on the distal end. The endoscope has a sheath which includes material having a sharp melting point slightly above body temperature so that the sheath may be made flexible at selected sections by applying current to separate heating wires in the sections of the sheath.

US Patent:

43212999, Mar 23, 1982

Filed:

Dec 21, 1979

Appl. No.:

6/106188

Inventors:

Robert A. Administrator of the National Aeronautics and Space Frosch
Robert E. Frazer - La Canada CA

International Classification:

B05D 500
B05D 506
B32B 1508
B32B 3112
B32B 3300

US Classification:

428247

Abstract:

Production of strong lightweight membrane structure by applying a thin reflective coating such as aluminum to a rotating cylinder, applying a mesh material such as nylon over the aluminum coating, coating the mesh overlying the aluminum with a polymerizing material such as a para-xylylene monomer gas to polymerize as a film bound to the mesh and the aluminum, and applying an emissivity increasing material such as chromium and silicon monoxide to the polymer film to disperse such material colloidally into the growing polymer film, or applying such material to the final polymer film, and removing the resulting membrane structure from the cylinder. Alternatively, such membrane structure can be formed by etching a substrate in the form of an organic film such as a polyimide, or a metal foil, to remove material from the substrate and reduce its thickness, applying a thin reflective coating such as aluminum on one side of the substrate and applying an emissivity increasing coating such as chromium and silicon monoxide on the reverse side of the substrate.

US Patent:

46920030, Sep 8, 1987

Filed:

Nov 7, 1983

Appl. No.:

6/549157

Inventors:

Iwao P. Adachi - Westminster CA
Yoshifumi Adachi - Westminster CA
Robert E. Frazer - La Canada CA

International Classification:

A61B 310

US Classification:

351212

Abstract:

A computer assisted keratometer in which a fiducial line pattern reticle illuminated by CW or pulsed laser light is projected on a corneal surface through lenses, a prismoidal beamsplitter quarterwave plate, and objective optics. The reticle surface is curved as a conjugate of an ideal corneal curvature. The fiducial image reflected from the cornea undergoes a polarization shift through the quarterwave plate and beamsplitter whereby the projected and reflected beams are separated and directed orthogonally. The reflected beam fiducial pattern forms a moire pattern with a replica of the first recticle. This moire pattern contains transverse aberration due to differences in curvature between the cornea and the ideal corneal curvature. The moire pattern is analyzed in real time by computer which displays either the CW moire pattern or a pulsed mode analysis of the transverse aberration of the cornea under observation, in real time. With the eye focused on a plurality of fixation points in succession, a survey of the entire corneal topography is made and a contour map or three dimensional plot of the cornea can be made as a computer readout in addition to corneal radius and refractive power analysis.

US Patent:

41301129, Dec 19, 1978

Filed:

Nov 15, 1976

Appl. No.:

5/741749

Inventors:

Robert E. Frazer - La Canada CA

Assignee:

The United States of America as represented by the Administrator of the
National Aeronautics and Space Administration - Washington DC

International Classification:

A61B 1000

US Classification:

128 2V

Abstract:

Apparatus for the ultrasonic scanning of a breast or other tissue, including a cavity for receiving the breast, a vacuum for drawing the breast into intimate contact with the walls of the cavity, and transducers coupled through a fluid to the cavity to transmit sound waves through the breast. Each transducer lies at the end of a tapered chamber which has flexible walls and which is filled with fluid, so that the transducer can be moved in a raster pattern while the chamber walls flex accordingly, with sound transmission always occurring through the fluid.

US Patent:

43866026, Jun 7, 1983

Filed:

May 17, 1977

Appl. No.:

5/797843

Inventors:

Charles H. Sheldon - San Marino CA
Robert E. Frazer - La Canada CA
Harold R. Lutes - Pasadena CA

International Classification:

A61B 100

US Classification:

128 4

Abstract:

Apparatus for operating on the brain with minimal disturbances thereto, including a bullet-shaped expandable device with an end that can be closed for insertion through a small hole in the brain. The device can be expanded after insertion to leave an air pocket through which to extend viewing and cutting devices which enable operation on tumors or the like that lie at the end of the expanded device. A set of probes of varying diameters are also provided, to progressively enlarge a passage leading to the tumor, prior to inserting the expandable device.