Robert W Hillman

US Patent:

53007794, Apr 5, 1994

Filed:

Aug 18, 1992

Appl. No.:

7/931719

Inventors:

Robert S. Hillman - Cupertino CA
Michael E. Cobb - Sunnyvale CA
Jimmy D. Allen - Los Altos CA
Ian Gibbons - Menlo Park CA
Vladimir E. Ostoich - San Jose CA
Laura J. Winfrey - Belmont CA

Assignee:

Biotrack, Inc. - Fremont CA

International Classification:

G01N 2149
G01N 3122

US Classification:

250341

Abstract:

Novel methods and devices are provided involving at least one chamber, at least one capillary, and at least one reagent involved in a system providing for a detectable signal. As appropriate, the devices provide for measuring a sample, mixing the sample with reagents, defining a flow path, and reading the result. Of particular interest is the use of combinations of specific binding pair members which result in agglutination information, where the resulting agglutination particles may provide for changes in flow rate, light patterns of a flowing medium, or light absorption or scattering. A fabrication technique particularly suited for forming internal chambers in plastic devices is also described along with various control devices for use with the basic device.

US Patent:

50049232, Apr 2, 1991

Filed:

Jan 30, 1990

Appl. No.:

7/472130

Inventors:

Robert S. Hillman - Cupertino CA
Michael E. Cobb - Sunnyvale CA
Jimmy D. Allen - Los Altos CA
Ian Gibbons - Menlo Park CA
Vladimir E. Ostoich - San Jose CA
Laura J. Winfrey - Belmont CA

Assignee:

Biotrack, Inc. - Mountain View CA

International Classification:

G01N 2149
G01N 2105

US Classification:

250341

Abstract:

Novel methods and devices are provided involving at least one chamber, at least one capillary, and at least one reagent involved in a system providing for a detectable signal. As appropriate, the devices provide for measuring a sample, mixing the sample with reagents, defining a flow path, and reading the result. Of particular interest is the use of combinations of specific binding pair members which result in agglutination information, where the resulting agglutination particles may provide for changes in flow rate, light patterns of a flowing medium, or light absorption or scattering. A fabrication technique particularly suited for forming internal chambers in plastic devices is also described along with various control devices for use with the basic device.

US Patent:

57332592, Mar 31, 1998

Filed:

Dec 22, 1994

Appl. No.:

8/363863

Inventors:

Christian P. Valcke - Los Angeles CA
Walter J. Bochenko - Encinitas CA
Robert S. Hillman - San Diego CA

Assignee:

Gensia Pharmaceuticals, Inc. - San Diego CA

International Classification:

A61M 500

US Classification:

604 66

Abstract:

A closed-loop drug delivery system uses patient response and rule based decision making methods to achieve operator specified responses for diagnostic purposes. In the preferred embodiment, cardiac diagnosis is performed by pharmacologically stressing the heart by administration of an exercise simulating agent drug. In the preferred method, a protocol is defined, which preferably includes a target for a physiologic variable, such as heart rate, and a plan to achieve that target value. Preferably, the plan includes a specification of the desired rate of increase in that variable, such as the rate of increase in the heart rate per minute. The plan comprises the desired changes in the physiologic variable as a function of time. While any desired function may be used, the more common modes include RAMP, HOLD, LEVEL and TARGET mode. In one aspect of this invention, the protocol may be varied by the operator after drug administration has begun.

US Patent:

47124601, Dec 15, 1987

Filed:

Nov 18, 1985

Appl. No.:

6/798780

Inventors:

Jimmy D. Allen - Los Altos CA
Michael E. Cobb - San Jose CA
Robert S. Hillman - Cupertino CA
Dennis R. Mungall - Redwood City CA
Vladimir E. Ostoich - San Jose CA
Gary H. Stroy - Los Altos CA

Assignee:

Biotrack, Inc. - Mt. View CA

International Classification:

B65D 8300

US Classification:

83208

Abstract:

An automatic drug tape dispensing and metering device and a roll of drug tape housed in a small portable dispenser unit. The dispenser contains a measurement device for carefully measuring the length of tape as it is dispensed from the dispenser. A counter monitors the remaining doses of drug tape remaining within the dispenser. A timer device may be provided to alert the patient that it is time for the medicament to be dispensed. As the lid of the dispenser unit is opened, the measured length of drug tape is severed from the roll by a cutter blade incorporated into the lid. The device permits a physician to accurately customize the dosage and administration of the medicament to be givne a patient by adjusting the tape length released for each single dose and selecting the time intervals between dosages.

US Patent:

51357194, Aug 4, 1992

Filed:

Oct 23, 1990

Appl. No.:

7/607618

Inventors:

Robert S. Hillman - Cupertino CA
Ian Gibbons - Menlo Park CA

Assignee:

Biotrack, Inc. - Mountain View CA

International Classification:

G01N 118
G01N 2101

US Classification:

422101

Abstract:

A method for separating plasma from red blood cells and a device utilizing the method in which a low-pressure filter is interposed in a pathway between an inlet port and a reaction area. The sole driving force for the movement of plasma from the filter to the reaction area is capillary force provided by a tubular capillary. The filter is selected from glass microfiber filters of specified characteristics, which can operate in the absence of agglutinins, and filters capable of separating agglutinated red cells from plasma, which require the use of an agglutinin.

US Patent:

51401614, Aug 18, 1992

Filed:

Jul 23, 1991

Appl. No.:

7/734597

Inventors:

Robert S. Hillman - Cupertino CA
Michael E. Cobb - Sunnyvale CA
Jimmy D. Allen - Los Altos CA
Ian Gibbons - Menlo Park CA
Vladimir E. Ostoich - San Jose CA
Laura J. Winfrey - Belmont CA

Assignee:

Biotrack - Mountain View CA

International Classification:

G01N 2149
G01N 3122

US Classification:

250341

Abstract:

Novel methods and devices are provided involving at least one chamber, at least one capillary, and at least one reagent involved in a system providing for a detectable signal. As appropriate, the devices provide for measuring a sample, mixing the sample with reagents, defining a flow path, and reading the result. Of particular interest is the use of combinations of specific binding pair members which result in agglutination information, where the resulting agglutination particles may provide for changes in flow rate, light patterns of a flowing medium, or light absorption or scattering. A fabrication technique particularly suited for forming internal chambers in plastics devices is also described along with various control devices for use with the basic device.

US Patent:

D322943, Jul 18, 1989

Filed:

Oct 3, 1986

Appl. No.:

6/915329

Inventors:

Robert S. Hillman - Cupertino CA

Assignee:

Biotrack, Inc. - Mountain View CA

US Classification:

D24 21

US Patent:

47972831, Jan 10, 1989

Filed:

Sep 23, 1987

Appl. No.:

7/100123

Inventors:

Jimmy D. Allen - Los Altos CA
Michael E. Cobb - San Jose CA
Robert S. Hillman - Cupertino CA
Dennis R. Mungall - Redwood City CA
Vladimir E. Ostoich - San Jose CA
Gary H. Stroy - Los Altos CA

Assignee:

Biotrack, Incorporated - Mountain View CA

International Classification:

A61K 970

US Classification:

424443

Abstract:

An automatic drug tape dispensing and metering device and a roll of drug tape housed in a small portable dispenser unit. The dispenser contains a measurement device for carefully measuring the length of tape as it is dispensed from the dispenser. A counter monitors the remaining doses of drug tape remaining within the dispenser. A timer device may be provided to alert the patient that it is time for the medicament to be dispensed. As the lid of the dispenser unit is opened, the measured length of drug tape is severed from the roll by a cutter blade incorporated into the lid. The device permits a physician to accurately customize the dosage and administration of the medicament to be given a patient by adjusting the tape length released for each single dose and selecting the time intervals between dosages.