Robert S Horton

US Patent:

20200157487, May 21, 2020

Filed:

Jan 22, 2020

Appl. No.:

16/749186

Inventors:

- Visp, CH
Matthew Sarcopski - Atlanta GA, US
Robert Horton - Lee NH, US
Thomas Ellis - Stratham NH, US
Paul Pease - Durham NH, US
John Chapin - Portsmouth NH, US

International Classification:

C12M 1/36
G01N 30/86
C12Q 3/00

Abstract:

The disclosure is directed to a system and method for control of at least one bioreactor, other cell cultivation-related equipment, and systems containing any combination of these in a plant. For example, a Plant-Wide Control System (PWCS) or a Process Control System (PCS) may be divided into three main components: hardware (including operating systems, such as a controller communicating with one or more servers of a network associated with the PWCS, (2) software (such as a control module) for performing control, and (3) one or more instrument control loops, which may be used by the software to maintain certain process values. Moreover, a Height Equivalent of a Theoretical Plate (HETP) value and an asymmetry factor may be determined based on real-time analysis on a chromatography column, using PWCS components.

US Patent:

20170107476, Apr 20, 2017

Filed:

Oct 14, 2016

Appl. No.:

15/294152

Inventors:

- Basel, CH
Matthew SARCOPSKI - Atlanta GA, US
Robert HORTON - Lee NH, US
Thomas ELLIS - Stratham NH, US
Paul PEASE - Durham NH, US
John CHAPIN - Portsmouth NH, US

International Classification:

C12M 1/36
G01N 30/86
C12Q 3/00

Abstract:

The disclosure is directed to a system and method for control of at least one bioreactor, other cell cultivation-related equipment, and systems containing any combination of these in a plant. For example, a Plant-Wide Control System (PWCS) or a Process Control System (PCS) may be divided into three main components: hardware (including operating systems, such as a controller communicating with one or more servers of a network associated with the PWCS, (2) software (such as a control module) for performing control, and (3) one or more instrument control loops, which may be used by the software to maintain certain process values. Moreover, a Height Equivalent of a Theoretical Plate (HETP) value and an asymmetry factor may be determined based on real-time analysis on a chromatography column, using PWCS components.