Robert L Kaufman

US Patent:

7119121, Oct 10, 2006

Filed:

Aug 25, 2005

Appl. No.:

11/212330

Inventors:

John Gregory Slatter - Bellevue WA, US
Raymond Charles Grabiak - Maryland Heights MO, US
Robert John Kaufman - University City MO, US

Assignee:

Pfizer Inc. - New York NY

International Classification:

A61K 31/13
C07C 211/00

US Classification:

514648, 564315, 564316

Abstract:

Novel 3,3-diphenylpropylamines of the formulaand stereoisomers and physiologically acceptable acid addition salt thereof; wherein R, R, R, R, R, and Rare as defined herein; methods of use thereof; and pharmaceutical compositions thereof.

US Patent:

7291648, Nov 6, 2007

Filed:

Aug 24, 2006

Appl. No.:

11/466814

Inventors:

John Gregory Slatter - Bellevue WA, US
Raymond Charles Grabiak - Maryland Heights MO, US
Robert John Kaufman - University City MO, US

Assignee:

Pfizer Inc. - New York NY

International Classification:

A61K 31/13
C07C 211/00

US Classification:

514648, 564315, 564316

Abstract:

Novel 3,3-diphenylpropylamines of the formula.

US Patent:

7387327, Jun 17, 2008

Filed:

Jun 24, 2005

Appl. No.:

11/165945

Inventors:

Allan Tencer - Seattle WA, US
Robert Philip Kaufman - Seattle WA, US
Charles Newman Mock - Seattle WA, US

Assignee:

University of Washington - Seattle WA

International Classification:

B60N 2/06
B60N 2/427

US Classification:

296 681, 296 6511, 296 6513, 29618712, 280751, 2972161, 29721618

Abstract:

A system for managing an occupant in an occupant compartment of an automotive vehicle, a structure for use in an automobile, and methods of use thereof are provided for protecting an occupant during a near side impact collision.

US Patent:

20050004223, Jan 6, 2005

Filed:

Apr 26, 2004

Appl. No.:

10/832555

Inventors:

John Slatter - Bellevue WA, US
Raymond Charles Grabiak - Maryland Heights MO, US
Robert Kaufman - University City MO, US

International Classification:

A61K031/195
A61K031/137

US Classification:

514567000, 514649000, 562442000, 564336000

Abstract:

Novel 3,3-diphenylpropylamines of the formula and any stereoisomers thereof; wherein Rrepresents —H or —CH; Rrepresents —CX, —CRX, —CRRX, or —CRRH, wherein X represents halogen, and Rand Rindependently represent —H or —(C-Calkyl), optionally substituted with halogen; Rand Rindependently represent —H, —OCH, —OH, —CONH, —SONH, —F, —Cl, —Br, —I, —CF, or —(C-Calkyl), optionally substituted with one or two —OH, —(C-Calkoxy), —COOH, or —CO—O—(C-Calkyl); and Rand Rindependently represent C-Calkyl, optionally substituted with hydroxyl, wherein Rand Rtogether contain at least three carbon atoms, and wherein Rand Rmay form a ring together with the amine nitrogen; provided that Rcomprises at least one halogen; or a physiologically acceptable acid addition salt thereof; the 3,3-diphenylpropylamines for use as medicaments, use of the 3,3-diphenylpropylamines for the manufacture of specific medicaments, and pharmaceutical compositions comprising the 3,3-diphenylpropylamines. The present invention also includes a method of treatment involving administration of the 3,3-diphenylpropylamines.