Robert B Levine

US Patent:

6695768, Feb 24, 2004

Filed:

Mar 29, 2000

Appl. No.:

09/538328

Inventors:

Robert A. Levine - New York NY 10024
Nadia Nathan - Wayland MA 01778
Mark Handschumacher - Boston MA 02114
J. Luis Guerrero - Norton MA 02766

International Classification:

A61F 200

US Classification:

600 37

Abstract:

This device aims at correcting distortions in spatial geometry and function of the heart muscle, thereby restoring valvular integrity and optimizing myocardial performance. The device is applied externally to the heart, fixed in the chest cavity or wall, while maintaining flexibility and selectively targeting specific points of varying size, tension, and force requirements. This minimally invasive device and method of application will contribute toward a reduced rate of mortality and morbidity from heart disease.

US Patent:

8472693, Jun 25, 2013

Filed:

Mar 18, 2011

Appl. No.:

13/051705

Inventors:

Graham Davis - Princeton NJ, US
Stephen C. Wardlaw - Lyme CT, US
Robert A. Levine - Guilford CT, US
Darryn W. Unfricht - North Haven CT, US
Niten Lalpuria - Mumbai, IN
Paul G. Mitsis - Trenton NJ, US

Assignee:

Abbott Point of Care, Inc. - Princeton NJ

International Classification:

G06K 9/00

US Classification:

382134

Abstract:

A method and apparatus for determining at least one hemoglobin related parameter of a whole blood sample is provided. The method includes the steps of: a) depositing the sample into an analysis chamber adapted to quiescently hold the sample for analysis, the chamber defined by an interior surface of a first panel, and an interior surface of a second panel, and the chamber has a height extending between the interior surfaces of the panels, wherein the chamber is configured to increase the oxygenation state of the sample to a substantially oxygenated state within a predetermined amount of time after entry into the chamber; b) imaging the at least one red blood cell contacting the interior surfaces, and producing image signals; c) determining an optical density of at least a portion of the imaged red blood cell contacting both interior surfaces; and d) determining the at least one hemoglobin related parameter of the red blood cell contacting the interior surfaces, using the determined optical density and a molar extinction coefficient for oxygenated hemoglobin.

US Patent:

20060292440, Dec 28, 2006

Filed:

Feb 7, 2006

Appl. No.:

11/349390

Inventors:

Robert Levine - Delray Beach FL, US

International Classification:

H01M 2/10

US Classification:

429099000, 429123000

Abstract:

A portable power supply unit having in combination, a supporting box having a cavity arranged for receiving two batteries, two electric batteries removably disposed in said cavity, a cover to securely contain such batteries in said box, solid embedded circuits electrically contacting said batteries in either parallel or series voltage contained with in the box, and means for accessing the current from outside the box.

US Patent:

20110244581, Oct 6, 2011

Filed:

Mar 31, 2011

Appl. No.:

13/077476

Inventors:

Igor Nikonorov - Whitestone NY, US
Niten V. Lalpuria - Mumbai, IN
Jeremy Hill - Guilford CT, US
John Wieners - Morrisville PA, US
Anil S. Patil - Iselin NJ, US
Robert Levine - Guilford CT, US
Benjamin Ports - Hamden CT, US
Darryn Unfricht - North Haven CT, US

Assignee:

Abbott Point of Care, Inc. - Princeton NJ

International Classification:

G01N 21/75

US Classification:

436 43, 422400

Abstract:

An apparatus for and method of analyzing a biologic fluid sample is provided. The method includes the steps of: a) providing a sample cartridge having at least one channel for fluid sample passage; b) providing an analysis device having imaging hardware, a programmable analyzer, and a sample motion system, which sample motion system includes a bidirectional fluid actuator operable to selectively move a bolus of sample axially within the channel, and to cycle the bolus back and forth within the channel; and c) cycling the bolus of sample disposed within the channel at a predetermined frequency until constituents within the sample are substantially uniformly distributed, using the bidirectional fluid actuator.

US Patent:

20130170729, Jul 4, 2013

Filed:

Nov 9, 2012

Appl. No.:

13/673644

Inventors:

Abbott Point of Care, Inc. - Princeton NJ, US
Robert A. Levine - Guilford CT, US
Darryn W. Unfricht - North Haven CT, US
Niten V. Lalpuria - Mumbai, IN
Jeremy R. Hill - Guilford CT, US

Assignee:

ABBOTT POINT OF CARE, INC. - Princeton NJ

International Classification:

G06T 7/00

US Classification:

382134

Abstract:

A method and apparatus for identifying reticulocytes within a blood sample is provided. The method includes the steps of: a) depositing the sample into an analysis chamber adapted to quiescently hold the sample for analysis, and the chamber has a known or determinable height extending between the interior surfaces of panels, which height is such that at least one red blood cell, or an aggregate of red blood cells, within the sample contacts both of the interior surfaces; b) admixing a supravital dye with the sample, which dye is operable to cause reticulin to fluoresce when excited by light of one or more predetermined wavelengths; c) imaging the sample using light that includes the one or more predetermined wavelengths that cause reticulin to fluoresce; d) imaging the sample using light that is absorbed by hemoglobin to produce values of optical density on a per image unit basis; and e) identifying reticulocytes within the sample using the image of the sample created with light that causes the dyed reticulin to fluoresce, and using the per image unit optical density values.

US Patent:

47749652, Oct 4, 1988

Filed:

Jul 1, 1987

Appl. No.:

7/068572

Inventors:

Rodolfo R. Rodriguez - Randolph NJ
Charles F. Galanaugh - West Milford NJ
Robert A. Levine - Guilford CT
Stephen C. Wardlaw - Old Saybrook CT
Theodore Juraschek - Wyckoff NJ

Assignee:

Becton Dickinson and Co., Inc. - Parsippany NJ

International Classification:

A61B 514

US Classification:

128771

Abstract:

A centrifuge tube is used to hold a mixture of several constituents, and also contains a generally cylindrical float. The float settles, after centrifugation, into the zone occupied by the constituent whose volume is to be measured. The constituent layer will settle, after centrifugation, into the annular space between the tube bore and the outside of the float, and will be expanded axially due to the restricted volume of the annular space. The degree of expansion is dependent upon the respective sizes of the float O. D. and the tube bore ID, both of which must be closely controlled for accurate results. A known volume of a control material is placed in the tube to settle into the annular space during centrifugation in an area thereof outside of the constituent layer zone. The length of the band of the control material is measured after centrifugation and is compared to a known length which will result if the annular space is of the proper target volume. A correction factor is thus obtained and applied to all of the other constituent layers which were measured.

US Patent:

46012036, Jul 22, 1986

Filed:

Jul 1, 1985

Appl. No.:

6/751242

Inventors:

Robert A. Levine - Westminster CA
Danny F. Davis - Westminster CA
Anthony W. Cordeiro - Huntington Beach CA

Assignee:

Atlantic Richfield Company - Los Angeles CA

International Classification:

G01N 2700

US Classification:

73432R

Abstract:

An oxygen content sampling system is disclosed. The system includes an oxygen probe and monitor. The oxygen probe and interconnecting cable pass through a housing adapted to receive and protect the probe during periods of non-use.

US Patent:

D2496283, Sep 26, 1978

Filed:

Oct 26, 1976

Appl. No.:

5/735674

Inventors:

Robert F. Levine - Marina Del Rey CA

International Classification:

D0606

US Classification:

D 8 1