Robert S Mccaffrey

US Patent:

D552593, Oct 9, 2007

Filed:

Oct 11, 2005

Appl. No.:

29/240161

Inventors:

Dirk Ahlgrim - Cambridge MA, US
Thomas Brisebras - La Balme de Sillingy, FR
Robert J. McCaffrey - Hillsborough NH, US
Gerd Schmieta - Boxton MA, US

Assignee:

Altec Lansing, a division of Plantronics, Inc. - Milford PA

International Classification:

1401

US Classification:

D14168, D14496

US Patent:

20050240119, Oct 27, 2005

Filed:

Apr 15, 2005

Appl. No.:

11/106728

Inventors:

Gregg Draudt - Slow MA, US
Dirk Ahlgrim - Boston MA, US
Jan Schminke - Munchen, DE
Mark Follman - Glen Rock NJ, US
Jose Colucci - Lexington MA, US
Raymond Yao - Saint Joseph MI, US
Robert McCaffrey - Hillsboro NH, US
Victor Chan - Landing NJ, US

International Classification:

A61B005/00
C12Q001/48

US Classification:

600583000, 435015000

Abstract:

A blood glucose meter having a test strip port and an adjustable lancet device disposed at the same end of the device body is disclosed. The device body further includes an enclosure at the proximal end of the device body which houses a test strip storage vial and which facilitates one-handed opening and closing of the vial to simplify access to test strips contained therein. The enclosure is further provided with a window which allows the reading of the lot numbers on the label of the test strip vial therein without necessitating removal of the vial. A data connector is also provided on the device body for communication access, such as to upload data from other devices or to download data to other devices. By combining these multiple components into a single device body, the blood glucose meter requires fewer steps for sampling and testing, and makes device use easier and more convenient.

US Patent:

20110226772, Sep 22, 2011

Filed:

Mar 22, 2010

Appl. No.:

12/728482

Inventors:

Ari Tao Adler - Cambridge MA, US
Robert John McCaffrey - Hillsborough NH, US

Assignee:

Wyeth LLC - Madison NJ

International Classification:

B65D 45/00

US Classification:

220315

Abstract:

Child-resistant bulk dose dispensing packaging unit, and a method for opening the packaging unit, including a container and a lid engaged with the container. The container includes a reservoir, an aperture at a top end of the reservoir, and a protrusion extending from a surface of the container. The lid engages with the container and slides between a closed position and an open position. The lid includes a top wall, a side wall extending down from an outer edge of the top wall, and a post configured to engage the protrusion at a first position when the lid is closed so as to keep the lid closed. At least a portion of the post extends substantially parallel to the side wall at a distance from the side wall. Pressing the side wall inward places the post at a second position, wherein at the second position the post is disengaged from the protrusion.

US Patent:

56016948, Feb 11, 1997

Filed:

Jul 27, 1995

Appl. No.:

8/508276

Inventors:

Thomas C. Maley - Medway MA
Paul A. D'Orazio - Mendon MA
Bonnie C. Dalzell - Sherborn MA
Peter G. Edelman - Franklin MA
James E. Flaherty - Attleboro MA
Richard W. Mason - Millis MA
Robert R. McCaffrey - Franklin MA

Assignee:

Ciba Corning Diagnostics Corp. - Medfield MA

International Classification:

G01N 2726

US Classification:

204415

Abstract:

A solid shale, multi-use electrochemical sensor having an electrically nonconductive substrate, a working electrode, and a semi-permeable membrane covering the working electrode. The working electrode includes an electrically conductive material adhered to a portion of the substrate. A first portion of the conductive material is covered with an electrically insulating dielectric coating, and a second portion of the conductive material is covered with an active layer. The active layer includes a catalytically active quantity of an enzyme carried by platinized carbon powder particles, which are distributed throughout the active layer. A sensor package for incorporating a sensor is provided.

US Patent:

57118680, Jan 27, 1998

Filed:

Sep 15, 1995

Appl. No.:

8/508275

Inventors:

Thomas C. Maley - Medway MA
Paul A. D'Orazio - Mendon MA
Bonnie C. Dalzell - Sherborn MA
Peter G. Edelman - Franklin MA
James E. Flaherty - Attleboro MA
Richard W. Mason - Millis MA
Robert R. McCaffrey - Franklin MA

Assignee:

Chiron Diagnostics Corporatiion - E. Walpole

International Classification:

G01N 2726

US Classification:

2057825

Abstract:

A solid state, multi-use electrochemical sensor having an electrically nonconductive substrate, a working electrode, and a semi-permeable membrane covering the working electrode. The working electrode includes an electrically conductive material adhered to a portion of the substrate. A first portion of the conductive material is covered with an electrically insulating dielectric coating, and a second portion of the conductive material is covered with an active layer. The active layer includes a catalytically active quantity of an enzyme carried by platinized carbon powder particles, which are distributed throughout the active layer. A sensor package for incorporating a sensor is provided.

US Patent:

55736475, Nov 12, 1996

Filed:

Sep 15, 1995

Appl. No.:

8/508270

Inventors:

Thomas C. Maley - Medway MA
Mark W. Boden - Millbury MA
Paul A. D'Orazio - Mendon MA
Bonnie C. Dalzell - Sherborn MA
Peter G. Edelman - Franklin MA
James E. Flaherty - Attleboro MA
Robert B. Green - Hopkinton MA
Steven C. Lepke - Danvers MA
Richard W. Mason - Millis MA
Robert R. McCaffrey - Franklin MA
John A. Zalenski - Mendon MA

Assignee:

Ciba Corning Diagnostics Corp. - Medfield MA

International Classification:

G01N 2726

US Classification:

204406

Abstract:

A solid state, multi-use electrochemical sensor having an electrically nonconductive substrate, a working electrode, and a semi-permeable membrane covering the working electrode. The working electrode includes an electrically conductive material adhered to a portion of the substrate. A first portion of the conductive material is covered with an electrically insulating dielectric coating, and a second portion of the conductive material is covered with an active layer. The active layer includes a catalytically active quantity of an enzyme carried by platinized carbon powder particles, which are distributed throughout the active layer. A sensor package for incorporating a sensor is provided.

US Patent:

57075026, Jan 13, 1998

Filed:

Jul 12, 1996

Appl. No.:

8/680050

Inventors:

Robert McCaffrey - Franklin MA
Katarina Tkacik - Concord MA
Brian Holman - Medfield MA
James Flaherty - Attleboro MA
Josef Brown - Salem NH
Peter Edelman - Franklin MA

Assignee:

Chiron Diagnostics Corporation - E. Walpole MA

International Classification:

G01N 2726

US Classification:

204403

Abstract:

A sensor for measuring a concentration of an analyte in a solution. The sensor comprises a substrate layer, an electrode layer and an immobilized enzyme layer. The sensor further includes an enzyme/polymer layer and/or a hydrophobic layer. The enzyme/polymer layer includes an enzyme disposed within a polymer matrix. The hydrophobic layer is formed from a material that is more hydrophobic than the immobilized enzyme layer material. In certain embodiments, the sensor includes the enzyme/polymer layer and the hydrophobic layer disposed between the enzyme/polymer layer and the immobilized enzyme layer such that the enzyme/polymer layer is disposed along the hydrophobic layer within an area above the immobilized enzyme layer.

US Patent:

56679831, Sep 16, 1997

Filed:

Oct 24, 1994

Appl. No.:

8/327856

Inventors:

Allison L. Abel - Randolph MA
Paul A. D'Orazio - Mendon MA
Bonnie C. Dalzell - Sherborn MA
Robert R. McCaffrey - Franklin MA
Laura S. Uretsky - Milford MA

Assignee:

Chiron Diagnostics Corporation - Walpole MA

International Classification:

C12Q 154
C12Q 100
C12Q 126
C12Q 148

US Classification:

435 14

Abstract:

It has been found that imidazole and related buffers enhance the activity of certain preservatives, for example either (1) a mixture of 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one or (2) 5-bromo-5-nitro-1,3-dioxane, that are used in clinical diagnostic reagents. It has also been found that these buffers and certain surfactants, such as BRIJ 700 and related hydrophilic surfactants, enhance the precision and accuracy of enzyme biosensors.