- Brentford, GB Jason Michael Gillian - King of Prussia PA, US Donghui Qin - King of Prussia PA, US Robert Rahn McKeown - King of Prussia PA, US Glenn R. Williams - King of Prussia PA, US
International Classification:
C07D 498/04 C07C 309/19 C07C 309/66
US Classification:
5142305, 544105
Abstract:
The present invention relates to {2-(alkyl)-3-[2-(5-fluoro-4-pyrimidinyl)hydrazino]-3-oxopropyl}hydroxyformamide compounds of Formula (I):or pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions, processes for making and use of such compounds in the inhibition of bacterial peptide deformylase (PDF) activity and in treatment methods for bacterial infections.
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